摘要
目的采用中西医结合治疗涂阳肺结核患者,分析治疗过程中治疗组与对照组疗效和不良反应的差别。方法在2008～2011年度,将门诊就诊的748例涂阳肺结核患者随机分为治疗组(372例)和对照组(376例),两组化疗方案均按世界卫生组织推荐的2H_3R_3Z_E_3/4H_3R化疗方案治疗,治疗组同时加服补金片每天2次,每次5片,对比两组在治疗过程中疗效与不良反应的情况。结果根据世界卫生组织推荐的化疗时间,共用药6个月后痰菌转阴率治疗组100%,对照组99.46%(P<0.05);不良反应发生率治疗组5.38%,对照组7.71%(P<0.05)。结论中西医联合治疗涂阳肺结核疗效优于对照组并能显著降低化疗药物不良反应的发生,提高患者全程服药的依从性,提高治愈率。
Objective To Analyze the efficacy and adverse reactions in the course of the treatment with com- bination of traditional Chinese and Western medicine for smear-positive tuberculosis. Methods A total of 748 ca- ses of smear-positive tuberculosis were randomly divided into the treatment group （372） and control group （376）. The two groups were treated with 2H3R3Z3E3/4H3R chemotherapy recommended by the World Health Organiza- tion（WHO）, and the treatment group took 5 gold tablets twice a day at the same time. The curative effects and side effects in the two groups were compared. Results Six months after medication, the sputum negative conversion rate in the treatment group and control group were 100% and 99.46% （P〈0. 05）; the incidence of adverse reac- tions in the treatment group and control group were 5.38% and 7.71% （P〈0.05）. Gonclusions Combined Chi- nese and Western medicine in the treatment of smear-positive tuberculosis is effective and able to significantly reduce the occurrence of adverse effects of chemotherapy drugs.
出处
《国外医学（医学地理分册）》
CAS
2013年第2期120-121,132,共3页
Foreign Medical Sciences：Section of Medgeography
基金
中国结核病控制项目(No.1993-1997)
关键词
涂阳肺结核
中西医结合
不良反应
smear-positive pulmonary tuberculosis
combination of traditional Chinese and Western medicine,reduced adverse reactions
