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静脉用人免疫球蛋白在重症甲型流感患儿治疗的临床观察

Clinical observation on intravenous therapy with human immunoglobulin in severe H1N1 influenza in children
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摘要 目的 观察静脉用人免疫球蛋白治疗重症甲型流感患儿的临床疗效.方法 回顾性总结本院2009年8月至2012年12月确诊的24例重症甲型流感患儿病例,随机分为治疗组(12例)和对照组(12例),对照组予抗感染、抗病毒、雾化吸入等常规治疗,治疗组加于静脉用人免疫球蛋白治疗,对两组患儿疗效进行对照分析.结果 治疗组经治疗后,疗效明显优于对照组,两者比较,差异有统计学意义(P<0.05).结论 静脉用人免疫球蛋白治疗儿童甲型流感患儿有显著疗效,值得临床应用推广. Objective To observe the clinical effect of intravenous human immunoglobulin in treatment of severe H 1N 1 influenza in children.Methods 24 children with severe H1N1 influenza from August 2009 to December 2012 were randomly divided into treatment group (12 cases) and control group (12 cases),the control group only received routine treatment with such as anti infection,antiviral,atomizing inhalation,and so on.The treatment group used intravenous human immunoglobulin.The curative effects of two groups were compared and analyzed.Results After treatment,the curative effect of the treatment group was obviously better than that of the control group,the difference between the two group was statistically significant (P〈0.05).Conclusion There is significant effect of intravenous human immunoglobulin therapy in severe H1N1 influenza in children,worthy of clinical application.
出处 《国际医药卫生导报》 2013年第14期2171-2173,共3页 International Medicine and Health Guidance News
关键词 静脉用人免疫球蛋白 重症甲型流感 Intravenous human immunoglobulin Severe H 1N 1 influenza
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  • 1尹继君,鲍金慧,张云凤.大剂量丙种球蛋白治疗病毒性脑炎的临床研究[J].实用全科医学,2004,2(5):443-444. 被引量:4
  • 2胡亚美,江载芳.褚福棠实用儿科学[M].北京:人民卫生出版社,2002:1604.
  • 3李万镇.危重急症的诊断与治疗[M].北京:中国科学技术出版社,1995.115-120.
  • 4胡亚美,江载芳,诸福棠.实用儿科学.第7版.北京:人民卫生出版社,2003:1174-1184.
  • 5中华人民共和国卫生部.甲型H1N1流感诊疗方案[S].3版.2009.
  • 6Dharan NJ,aubareva LV,Meyer JJ,et al.Infections with oseltamivir-resistant influenza A(H1N1)virus in the United States[J].JAMA,2009,301(10):1034-1041.
  • 7Nichols JE,Niles JA,Roberts NJ Jr.Human lymphocyte apoptosis after exposure to influenza A vorus[J].J virol,2001,75(15):5921-5929.
  • 8Maddur,M.S.et al,Intravenous polyclona immunoglobulin in autoimmune diseases:clinical indications and mechanisms of action[J].Drug Discov Today,2009,10(3):2.
  • 9S.Siberil et al.Intravenous immunoglobulin in autoimmune and inflammatory diseases:More than mere transfer of antibodies[J].Transfusion and Apheresis Science,2007,37(5) 104-106.
  • 10Lam L,whitsett CF,Mc-Nicholl JM,et al.Immunologi-cally active proteins in intravenous immunoglobulin[J].Lancet,1993,342(8872):678-679.

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