摘要
目的:观察及分析采用肺泡表面活性物质联合气道持续正压通气治疗新生儿呼吸窘迫综合征的疗效。方法:分析66例患有新生儿呼吸窘迫综合征的患儿临床资料,救治方式为经鼻气道持续正压通气联合肺泡表面活性物质的37例为观察组和传统面罩通气联合肺泡表面活性物质的29例为对照组,对于两组患儿治疗前后各方面情况进行对比。结果:两组患儿经治疗后大多数临床症状均有明显改善,血气分析治疗前后差异有统计学意义(P<0.05),而组间比较差异无统计学意义(P>0.05)。观察组治疗总有效率为78.38%,对照组治疗总有效率为75.86%,两组差异无统计学意义(P>0.05)。并发症观察组少于对照组,差异有统计学意义(P<0.05)。两组患儿住院时间及治疗费用观察组优于对照组,差异有统计学意义(P<0.05)。结论:两种方式治疗新生儿呼吸窘迫综合征均可以有效起到治疗作用,而肺泡表面活性物质联合气道持续正压通气的方式与传统的联合面罩通气相比较,并发症发生率降低,住院时间及治疗费用降低。
Objective：To the presence of the neonatal respiratory distress syndrome,use the alveolar surface active substance combination nasal airway continuous positive airway pressure treatment method,observe and analyze the curative effect.Methods：Analysis of selection of treatment in our hospital 66 cases of clinical data of children with severe neonatal respiratory distress syndrome was executed,the alveolar surface active substance combination nasal airway continuous positive airway pressure was used in observation group and traditional mask ventilation alveolar surface active substances in control group.Various aspects condition of children in both groups before and after treatment were compared.Results：Most clinical symptoms of children in two groups were significantly improved after treatment,there was significant difference in blood gas analysis before and after treatment in both two groups（P0.05）,but there was no significant difference between two groups（P0.05）.Total effective rate was 78.38% in observation group,75.86% in control group,there was no significant difference between two groups（P0.05）.Complications in observation group were less than those of control group（P0.05）.Length of hospital stay and cost of treatment of observation group were better than those of control group（P0.05）.Conclusion：Two ways in the treatment of neonatal respiratory distress syndrome,both can have effective treatment effect.Compared with the combination of traditional mask ventilation,alveolar surface active substance combination nasal airway continuous positive airway pressure can reduce the incidence of complications,hospitalization time and lower treatment costs.
出处
《中国妇幼保健》
CAS
北大核心
2013年第20期3276-3278,共3页
Maternal and Child Health Care of China
基金
上海市浦东新区卫生局科技项目〔PW2009C-34〕
关键词
经鼻气道持续正压通气
面罩通气
肺泡表面活性物质
新生儿呼吸窘迫综合征
Nasal airway continuous positive airway pressure
Mask ventilation
Alveolar surface active substance
Neonatal respiratory distress syndrome
