摘要
肺癌是绝大多数国家死亡率最高的恶性肿瘤,早期诊断是早期治疗的重要条件。以胸部X片、螺旋CT、支气管内镜、痰细胞学等检查手段作为肺癌筛检手段进行早期诊断已有许多报道,但上述检查手段的敏感性、特异性、适用度等均有一定局限性,近年来肺癌早期诊断的分子生物标志物受到重视并已进行了大量有益的探索,本文拟就该领域的相关进展作一综述。
Lung cancer is the leading cause of cancer death in most countries. Early diagnosis is very important for early treatment. Chest X-ray, spiral CT, bronchoscopy and sputum cytology have long been used as screening or diagnostic modalities for early detection of lung cancer. However, these methods have limitations in sensitivity, specificity or utility in some degree. In recent years, both at home and abroad scholars have done a large amount of useful exploration on discovering and identifying molecular bio- markers for the early diagnosis of lung cancer. In this paper, recent progresses in this field are reviewed.
出处
《医学研究生学报》
CAS
北大核心
2013年第7期766-770,共5页
Journal of Medical Postgraduates
关键词
肺癌
早期诊断
分子生物标志物
Lung cancer
Early diagnosis
Molecular biomarker.
