摘要
目的探讨不同剂量的丙种球蛋白治疗重症手足口病患儿的疗效。方法选取2009年3月～2013年3月来院就诊的重症手足口病患儿97例,分为3组。在基础治疗的基础上,A组给予IVIG0.2g/(kg·d)治疗;B组予IVIG1g/(kg·d)治疗。C组予羚羊角粉治疗。结果 A、B两组患者NSS好转、发热缓解、临床治愈时间比较,差异均无统计学意义(P>0.05)。A、B两组与C组比较,NSS好转、发热缓解、临床治愈时间比较,差异均有统计学意义(P<0.05)。A、B两组治疗10d后复查脑脊液及心电图正常和异常率比较,差异均无统计学意义(P>0.05)。结论及早使用IVIG对手足口病患儿疗效显著;使用大、小剂量IVIG治疗重症手足口病疗效相近。
Objective To study the curative effect of children with different dose of gamma globulin in the treatment of severe hand-foot-mouth disease. Methods 97 cases in the hospital with severe hand foot and mouth disease in,from 2009 March to 2013 March were divided into 3 groups.On the basis of conventional treatment, A group was given IVIG 0.2g/（kg .d） treatment;group B was treated with IVIG lg/（kg .d） treatment.C group was treated with antelope horn powder. Results NSS improving, fever,alleviate clinical cure time comparison between A and Bgroup,the difference was not statistically significant（P 〉 0.05）.But NSS improved,fever,alleviate clinical cure time comparison among A,B two group and C group,the differences were statistically significant（P 〈 0.05）.A, B two groups after 10 d treatment cerebrospinal fluid and normal ECG and abnormal rate, the difference is not statistically significant（P 〉 0.05）. Conclusion Early use of IVIG significantly in children with hand-foot-and-mouth disease curative has effect;The use of large, small doses of IVIG had similar effect in treatment of severe hand-foot-mouth disease.
出处
《中国医药科学》
2013年第13期71-72,共2页
China Medicine And Pharmacy
关键词
丙种球蛋白
重症手足口病
疗效
Gamma globulin
Hand-foot-and-mouth disease
Curative effect
