摘要
目的研究AMI早期标志物心脏型脂肪酸结合蛋白（H-FABP）在AMI发生早期的变化及意义。方法回溯研究确诊为AMI的患者这项指标在入院后0~2h、2~4h、4~6h血清中的变化,用夹心ELISA方法定量检测H-FABP水平并与正常对照组比较。结果入院后2h内组即见H-FABP浓度明显高于正常对照组,且诊断符合率高达100%;2h以后组AMI病人100%H-FABP水平升高（P〈0.05）。结论 AMI早期检测H-FABP诊断价值高,且现有快速检测试剂,值得推广使用。
Objective To study the variation and clinical significance of heart-type fatty acid binding protein（H-FABP） at the early stage of AMI.Methods The levels of H-FABP were detected in 32 AMI patients using sandwich enzyme immunoassay at three time points,0~2 hours,2~4 hours,and 4~6 hours from admission.Results H-FABP in AMI patients displayed a higher level than control group within 2 hours after admission,and the diagnose coincidence rate of AMI was 100%.Two hours later,the concentration of H-FABP was still higher than control group（P0.05）.Conclusion Detection of H-FABP has a significant value in early diagnose of AMI.
出处
《实验与检验医学》
CAS
2013年第4期320-321,共2页
Experimental and Laboratory Medicine
基金
贵阳市卫生局立项课题(编号Y20110812)
关键词
心肌梗死
心脏型脂肪酸结合蛋白
标志物
Myocardial infarction
Heart-type fatty acid binding protein
Myocardial injury markers
