摘要
目的探讨免疫营养治疗对重型颅脑损伤患者康复的影响。方法根据营养治疗的不同将80例重型颅脑损伤患者分为对照组和观察组，各40例。两组患者均采用常规治疗，同时观察组给予免疫营养治疗，对照组给予常规营养治疗。观察治疗后第14天、第30天的营养状况，比较治疗3个月后两组患者的Barthel指数、Fugl-Meyer评分和神经功能恢复情况。结果两组治疗后血浆白蛋白（Alb）和转铁蛋白（TF）显著升高（t=5．75、6．38、1．27、2．63，均P〈0．05）；观察组的ALB和TF在治疗后第14天、第30天均显著高于对照组（t=11．26、6．53、1．27、1．68，均P〈0．05）。治疗3个月后两组比较，观察组临床疗效满意率（60.00％）好于对照组（37．50％）（X^2=9．67，P〈0．05），Barthel指数、Fugl-Meyer评分比较差异均有统计学意义（t=3．24、2．88，均P〈0．05）。结论免疫营养治疗可以显著促进重型颅脑损伤患者神经功能恢复，从而改善预后、提高患者的生存质量。
Objective To explore the influence of immune and nutrition therapy on the rehabilitation of pa- tients with severe traumatic brain injury. Methods According to the different nutritional therapy,80 patients with se- vere traumatic brain injury were divided into the control group and observation group, each group 40 eases. The pa- tients of the two groups were all given similarly conventional methods, and the observation group were given immune nutrition therapy ,the control group were given routine nutrition therapy. After 14d,30d treatment, nutritional status of the two groups were observed. Barthel Index, Fugl-Meyer score of the two groups of patients and recovery of neurologi- cal function were compared 3 months after treatment. Results After treatment, ALB and TF increased significantly （ t = 5.75,6.38,1.27,2.63, all P 〈 0.05 ） ; ALB and TF in the observation group 14 d and 30 d after treatment were significantly higher than those of the control group （ t = 11.26,6.53,1.27,1.68, all P 〈 0.05 ）. After 3 months of treatment between the two groups, the clinical efficacy of the observation group was 60.00%, which was better than that of control group （ 37.50% ） （ X^2 = 9.67, P 〈 0.05 ）, the differences of Barthel Index and, Fugl-Meyer score were statistically significant （ t = 3.24,2.88, all P 〈 0.05 ）. Conclusion The immune and nutritional therapy can signifi- cantly promote the neurological function recovery of patients with severe traumatic brain injury, so as to improve the prognosis and the patients＇s quality of life.
出处
《中国基层医药》
CAS
2013年第18期2786-2788,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
颅脑损伤
免疫
营养
预后
Craniocerebral trauma
Immunity, nutrition therapy
Prognosis
