期刊文献+

阴道镜与宫颈环形电切术在宫颈上皮内瘤变诊断和治疗中的应用价值比较 被引量:11

Application value of colposcopy and loop electrical excision procedure in diagnosis and treatment on cervical intraepithelial neoplasia
在线阅读 下载PDF
导出
摘要 目的比较宫颈上皮内瘤变(CIN)术前阴道镜下活组织检查结果与宫颈环形电切术(LEEP)后病理检查结果,评价阴道镜与LEEP在CIN诊断和治疗中的应用价值。方法对350例疑似CIN患者术前进行阴道镜下活组织检查病理诊断,并与LEEP术后组织病理检查结果进行对照比较。结果 350例手术均成功,阴道镜下活组织病理检查结果与LEEP术后病理检查结果完全符合率为72.57%,诊断过度率15.71%,诊断不足率11.71%。结论阴道镜下活组织检查可能遗漏CIN或早期浸润癌;LEEP可提供较完整的组织标本,可进一步筛查宫颈癌,有效弥补阴道镜的不足。 Objective To compare the biopsy result by colposcopy before operation and pathology result after loop electrical excision procedure(LEEP) in cervical intraepithelial neoplasia(CIN),and to evaluate the value of colposcopy and LEEP in diagnosis and treatment of CIN.Methods Biopsy by colposcopy before operation and biopsy after LEEP were analyzed and compared in 350 patients with skeptical CIN.Results The total coincidence rate of pathological results between cervical biopsy by colposcopy and LEEP was 72.57%,with 55 cases upgraded(15.71%) and 41 cases downgraded(11.71%).Conclusion The biopsy by colposcopy may miss the CIN or early invasive carcinoma;LEEP can provide a more complete specimens,and further screening cervical cancer,and redeem the lack of colposcopy effectively.
出处 《新乡医学院学报》 CAS 2013年第8期629-631,共3页 Journal of Xinxiang Medical University
基金 国家自然科学基金资助项目(编号:81101964 81172464) 湖北省自然科学基金资助项目(编号:2012FFB02421) "重大新药创新"科技重大专项项目(编号:2009ZX09103-739)
关键词 宫颈上皮内瘤样病变 阴道镜检查 宫颈环形电切术 cervical intraepithelial neoplasia colposcopy loop electrical excision procedure
  • 相关文献

参考文献8

  • 1蔡智慧,冯丽,刘梅云,张春英,孙谦.宫颈上皮内瘤变LEEP术前术后病理结果比较[J].中国误诊学杂志,2012,12(6):1343-1344. 被引量:3
  • 2张志胜.阴道镜图谱[M].2版.北京:人民卫生出版社,2002.1-10.
  • 3Stoler M H,Vichnin M D,Ferenczy A,et al.The accuracy of colpo-scopic biopsy:analyses from the placebo arm of the Gardasil clini-cal trials[J].Int J Cancer,2011,128(6):1354-1362.
  • 4吕卫国,沈源明,叶枫,陈怀增,谢幸.阴道镜直视下活检诊断宫颈上皮内瘤变准确性的评价[J].中华医学杂志,2006,86(5):303-306. 被引量:107
  • 5Siegler E,Bornstein J.Loop electrosurgical excision procedures inIsrael[J].Gynecol Obstet Invest,2011,72(2):85-89.
  • 6Singla S,Mathur S,Kriplani A,et al.Single visit approach for man-agement of cervical intraepithelial neoplasia by visual inspection&loop electrosurgical excision procedure[J].Indian J Med Res,2012,135(5):614-620.
  • 7杨春梅.阴道镜下活检与LEEP术病理分析对于宫颈上皮内瘤变的诊断价值[J].吉林医学,2012,33(1):13-14. 被引量:17
  • 8Duesing N,Schwarz J,Choschzick M,et al.Assessment of cervicalintraepithelial neoplasia(CIN)with colposcopic biopsy and effica-cy of loop electrosurgical excision procedure(LEEP)[J].Arch Gy-necol Obstet,2012,286(6):1549-1554.

二级参考文献17

  • 1吕卫国,沈源明,叶枫,陈怀增,谢幸.阴道镜直视下活检诊断宫颈上皮内瘤变准确性的评价[J].中华医学杂志,2006,86(5):303-306. 被引量:107
  • 2谢红,杨菊芳,马利国,王莉菲.宫颈上皮内瘤变阴道镜下活检与电环切除术后病理的对比分析[J].山西医科大学学报,2006,37(7):743-745. 被引量:4
  • 3Fambrini M, Penna C, Fallani MG, et al. Management of cervical intraepithelial neoplasia: the role of biopsy. Inter J Gynecol Obstet,2003,82:219-220.
  • 4Barker B, Gareia F, Lozevski J, et al. The correlation between colposcopically directed cervical biopsy and loop electrosurgical excision procedure pathology and the effect of time on that agreement. Gynecol Oncolk,2001,82 :22-26.
  • 5Massad LS, Halperin CJ, Bitterman P. Correlation between colposcopically directed biopsy and cervical loop excision. Gynecol Oncol, 1996,60:400-403.
  • 6Wright TC, Cox T, Massad LS, et al. 2001 consensus guidelines for the management of women with cervical intraepithelial neoplasia. Am J Obstet Gynecol, 2003,189:295 -304.
  • 7Costa S, Nuzzo MD, Rubino A, et al. Independent determinants of inaccuracy of colposcopically directed punch biopsy of the cervix.Gynecol Oncol,2003 ,90 :57-63.
  • 8Ostor AG. Natural history of cervical intraepithelial neoplasia: a critical review. Int J Gynecol Pathol, 1993,12 : 186-192.
  • 9Stoler MH, Schiffman M. Interobserver reproducibility of cervical cytologic and histologic interpretations: realistic estimates from the ASCUS-LSIL triage study. JAMA,2001,285 : 1500-1505.
  • 10何春年,徐翠清,赵焕芬,翟金萍,石卫东.宫颈上皮内瘤变及鳞癌诊治过程中病理分级及治疗探讨[J].实用妇产科杂志,2007,23(8):489-492. 被引量:18

共引文献135

同被引文献113

  • 1卞美璐.WHO(2006年)宫颈癌综合防治实践指南简介[J].中国实用妇科与产科杂志,2007,23(7):557-560. 被引量:106
  • 2张建新,张长淮,周艳秋,吴瑞芳.15393例宫颈液基细胞学与组织病理学的对照分析[J].中华病理学杂志,2007,36(7):485-488. 被引量:36
  • 3孟庆伟,秦振河,毛莹,赵晓东.冷刀锥切术切缘阴性的重度宫颈鳞状上皮内瘤变患者的预后影响因素分析[J].中华妇产科杂志,2007,42(7):457-459. 被引量:27
  • 4焦桂青,李建平.TCT检测及巴氏涂片细胞学检测在宫颈癌筛查中的对比研究[J].河北北方学院学报(医学版),2007,24(4):22-24. 被引量:5
  • 5Arbyn M,Castellsague X,de Sanjose S,et al. Worldwide burden of cervical cancer in 2008 [ J]. Ann Oncol, 2011,22 ( 12 ) : 2675- 2686.
  • 6Anttila A,Pukkala E,Soderman B,et al. Effect of organised scree- ning on cervical cancer incidence and mortality in Finland, 1963 - 1995 :recent increase in cervical cancer incidence[ J]. Int J Canc- er, 1999,83( 1 ) :59-65.
  • 7Pierce Campbell C M, Menezes L J, Paskett E D, et al. Preventionof invasive cervical cancer in the United States:past, present, and future[ J]. Cancer Epidemiol Biomarkers Prey ,2012,21 (9) : 1402- 1408.
  • 8Ward K K, Shah N R, Saenz C C, et al. Changing demographics of cervical cancer in the United States :1973 -2008 [ J]. Gynecol On- col,2012,126 ( 3 ) :330-333.
  • 9Miura S, Matsumoto K, Oki A, et al. Do we need a different strategy for HPV screening and vaccination in East Asia [J ]. lnt J Cancer, 2006,119(11) :2713-2715.
  • 10de Bekker-Grob E W, de Kok I M, Bulten J,et al. Liquid-based cervical cytology using thinprep technology:weighing the pros and cons in a cost-effectiveness analysis [ J ]. Cancer Causes Control, 2012,23(8) :1323-1331.

引证文献11

二级引证文献89

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部