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真菌性角膜炎的临床特征及疗效观察 被引量:69

The clinical features and study on therapeutic effects of fungal keratitis
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摘要 目的 回顾性分析真菌性角膜炎 (fungalkeratitis,FK)的临床特征及疗效。方法 将 110例 (110只眼 )FK患者按不同致病菌种类丝状菌 (94只眼 )及酵母菌 (16只眼 )型角膜炎进行分型。通过病史、检查结果及治疗情况等对两型角膜炎的临床特征及疗效进行观察和比较。结果 丝状菌型角膜炎患者多具有农作物外伤病史 ,病灶边界不清 ,边缘呈羽毛状 ,易向基质深层发展 ,常合并内皮斑及前房积脓 ,其治疗效果较差 ;酵母菌型角膜炎的发病与长期滴用糖皮质激素眼液有关 ,病灶局限、边缘清楚 ,较少向基质深层及眼内浸润 ,治疗效果较好。结论 丝状菌及酵母菌型角膜炎患者具有不同的临床特征 ,其不同致病真菌或同一致病真菌感染所引起的临床特征可有较大变异。早期诊断。 Objective To review the clinical features and therapeutic effects of fungal keratitis (FK) Methods 110 cases (110 eyes) with the disease were divided into two types: hyphomycetic keratitis in 94 eyes and candida keratitis in 16 eyes The clinical features and therapeutic effects of the two types were observed and compared Results The hyphomycetic keratitis generally had a plant traumatic history The border of corneal infiltration was not clear with feather edges, and had a tendency to penetrate into the deep stroma of cornea There were endothelial plaques, hypopyon and bad therapeutic effects The pathogenicity of cardida keratitis (CK) was related to the local long term use of glucocorticoid, the fungus seldom expanded into the deep corneal layers and infiltrated into the inner eye Its therapeutic effects were better The border of CK was characterized with limitations, and was clear Conclusions The clinical features of the two types are different The clinical features caused by different or the same pathogenic fungi show great variations Early diagnoses, correct use of medicine and operation are the key points to increase the curative rate
出处 《中华眼科杂志》 CAS CSCD 北大核心 2000年第5期358-361,共4页 Chinese Journal of Ophthalmology
关键词 丝状菌 酵母菌 临床特征 疗效 真菌性角膜炎 Eye infections, fungal Hyphomycetic keratitis Candida keratitis
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