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异丙酚麻醉在喉显微手术中的应用

APPLICATION OF PROPOFOL IN LARYNEAL MICROSURGERY
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摘要 目的 :观察喉显微手术应用异内酚为主的复合麻醉对循环功能的影响及术后清醒过程。方法 :2 6例病人随机分为两组。异丙酚组 ,诱导剂量为 2 m g/ kg;γ-羟基丁酸钠组 ,诱导剂量为 6 0 m g/ kg。监测诱导前、诱导后插管前、插管后 2 m in、置支撑喉镜手术时及术毕的血压和心率 ,记录术毕到清醒的时间及清醒后情况。结果 :异丙酚组诱导后插管前血压、心率均下降 (P <0 .0 1) ,插管后及术中血压、心率较诱导前变化不明显 ,术中循环功能较 γ-羟基丁酸钠组平稳 (P <0 .0 1) ,术后清醒时间较 γ-羟基丁酸钠组明显缩短 (P <0 .0 1)。结论 :异丙酚麻醉应用于喉显微手术有对术中循环功能影响小 ,术后苏醒快 ,质量好的优点 ,是比较理想的麻醉方法。 Objective:To observe the effect of propofol on circulation function and awareness period in laryneal microsurgery with propofol Compared with the effect of sodium hydroxybutyrate Methods:26 Patients were randomly divided into two groups:propofol group and sodium hydroxybutyrate group Induction doses were 2 mg/kg and 60 mg/kg respectively The changes of blood pressure and heart rate were observed before induction,after induction and before intubation,2 minutes after intubation,during operation with laryngoscopy,at the end of the operation The time from the end of the operation to postoperative awareness was recorded Somnolence,nausea and vomit were observed at the same time Results:In propofol group,both blood pressure and heart rate decreased after induction and bfeore intupbation Compared with sodium hydroxybutyrate group,the variety of circulation was not significant after intubation and during operation Postoperative awareness time was decreased significantly (P<0 01) No obvious somnlence,nausea and vomit were observed Conclusion:Propofol can keeps circulation function stable and patients aware rapidly and smoothly in laryneal microsurgery The application of propofol is an effective anesthetic method
作者 陈序 赵娟
出处 《广西医科大学学报》 CAS 2000年第5期796-797,共2页 Journal of Guangxi Medical University
关键词 异丙酚 Γ-羟基丁酸钠 喉显微手术 复合麻醉 propofol sodium hydroxybutyrate Laryneal microsurgery
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参考文献5

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