摘要
本文应用小鼠巴豆油诱发耳廓肿胀、慢性肉芽肿、醋酸致腹腔毛细血管通透性增加及豚鼠创伤性瘀斑实验 ,研究痛血康的抗炎、消肿祛瘀作用。结果表明 ,痛血康 1.0～ 3.0 g· kg- 1 ,ig;0 .0 5～ 0 .3g· kg- 1 ,SC显著抑制巴豆油诱发小鼠耳廓肿胀 ,慢性肉芽肿增生 ,具有明显抗炎作用 ;显著抑制醋酸致小鼠腹腔毛细血管通透性增加 ,促进创伤性瘀斑的消退。效应与剂量相关。
This paper reported the effects on antiinflammatory,eliminating swelling and dispersing blood clots of Tongxuekang(TXK).The results showed that TXK1.0～3.0 g.kg\+\{-1\},ig;0.05～0.30 g.kg\+\{-1\},sc,inhibited mice’s ears swell induced by croton oil and the increased of rats pelletgranuloma.It also inhibited considerably the increased vascular permeability induced by ip 0.7% HAc in mice and accelerated the elimination of traumatic blood clots on guinea pigs.The effect relative with the dosage.
出处
《海峡药学》
2000年第3期34-36,共3页
Strait Pharmaceutical Journal
关键词
痛血康
抗炎作用
中药
消肿祛瘀
小鼠
Tongxuekang(TXK)
Antiinflammatory effect
Pelletgranuloma,Blood clots
