摘要
目的 :观察13 1I治疗甲状腺功能亢进 (甲亢 )的近期临床疗效。方法 :选择适合13 1I治疗的病例 ,测定甲状腺吸13 1I率并行甲状腺显像 ,估算甲状腺的重量。根据经验公式并参考患者的病情、年龄、病程 ,确定较为确切的治疗量 ,采用一次性口服法。治疗后 3个月、6个月、12个月复诊。结果 :治疗 2 6 0例甲亢中 ,2 2 5例痊愈 ,治愈率达 86 .5 % ,16例未完全缓解者 ,其中 8例 1年后给予第二次13 1I治疗。随访 1年时发生甲状腺功能减低 (甲低 ) 19例 ,甲低发生率为 7.3%。甲低者口服甲状腺素片替代治疗 ,能维持甲状腺功能正常。结论 :13 1I治疗甲亢是一种安全、有效、复发率低的方法。
Objective:To investigate the immediate curative effect in treatment of hyperthyroidism with 131 I. Methods:Two hundred and sixty patients with hyperthyroidism and suitable for therapy with 131 I were singled out.Reliable therapeutic doses were determined on the basis of thyroid iodine 131 uptake,the weight of thyroid routine dose formula,the patients age,condition and course of disease. It was taken once orally. The patients came back to the hospital for a check in 3,6,12 months.Results:Among 260 cases of hyperthyroidism treated with 131 I,225 had restored health,the cure rate was 86.5%.Of the 16 cases who did not fully recovered,8 were given 131 I again one year later.Nineteen cases were found hypothyroidism in one year's follow up and the occurrence rate was 7.3%.Thyroid hormone replacement was performed to maintain thyroid function.Conclusions:It proves to be safe,effective,and of low recurrence to treat hyperthyroidism with 131 I. [
出处
《蚌埠医学院学报》
CAS
2000年第6期393-394,共2页
Journal of Bengbu Medical College