摘要
目的探讨改良换血疗法治疗新生儿重症高胆红素血症的临床疗效。方法对重症高胆红素血症患儿实行外周静动脉同步全自动换血疗法,比较换血前后患儿体内的胆红素、血常规指标以及临床检测指标的变化。结果总胆红素、直接胆红素、间接胆红素换血后较换血前均明显降低(P均<0.05)。血常规检测中,换血前后血红蛋白的变化较大(P<0.05),而K+、Ca2+、Cl-、Na+浓度及Plt、RBC变化不大(P均>0.05)。同时患儿换血前后体温、呼吸、心率和血压比较无显著性差异。结论改良换血疗法治疗新生儿重症高胆红素血症临床效果明显,易于操作,值得基层医院开展。
Objective It is to observe the clinical effect of improved exchange transfusion therapy in the treatment of neo- natal hyperbilirubinemia. Methods Neonates with hyperbilirubinemia were performed with peripheral vein-artery synchronized and automatically exchange transfusion therapy. The changes of bilirubin, blood routine indexes and clinical detection indica- tors before and after therapy were observed and compared. Results The levels of total bilirubin, direct bilirubin, indirect bili- rubin after therapy were markedly decreased （ all P 〈 0.05）. There was much change of Hb before and after therapy （P 〈 0. 05）. There was no significance difference in K＋ , Ca2 ＋ , Cl- , Na ＋ concentration and Ph, RBC before and after therapy （all P 〉 0.05）. There were no significant differences in body temperature, respiration, heart rate and blood pressure before and after therapy （ all P 〉 0.05）. Conclusion Improved high exchange transfusion therapy has obvious clinical effect for neo- natal hyperbilirubinemia, it is easy to operate, and is worthy to evolve in grassroots hospitals.
出处
《现代中西医结合杂志》
CAS
2013年第29期3201-3203,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
改良换血疗法
新生儿
高胆红素血症
improved exchange transfusion
neonatal
hyperbilirubinemia
