摘要
目的:评价慢性心功能不全(CHF)患者血清N端脑钠肽前体(NT-proBNP)和同型半胱氨酸(HCY)的意义。方法:对166例CHF患者和50例对照组,采用荧光偏振免疫分析法、电化学发光免疫技术分别测定HCY、NT-proBNP水平。结果:Ⅱ、Ⅲ、Ⅳ级CHF组与对照组比较,Ⅲ、Ⅳ与Ⅱ级CHF组比较,Ⅳ与Ⅲ级CHF组比较,CHF治疗前后比较,HCY和NT-proBNP水平均有显著性差异(P<0.01);CHF组HCY和NT-proBNP阳性率均显著高于对照组(P<0.05)。结论:检测血清HCY和NT-proBNP水平有助于诊断CHF和评估其严重程度,及评价其近期治疗效果,
Objective To Evaluate the detection and significance of serum N - terminal pro - brain natriuretic peptide （ NT - proBNP） and homocysteine （HCY） on chronic or congestive heart failure （CHF）. Methods： 166 patients with CHF and 50 conFol group, HCY and NT - proBNP level were measured by fluorescence polarization immunoassay and electrochemiluminescence immunoassay technology respec-tively. Results：Compared Ⅱ, Ⅲ and IV level CHF group and normal control group, Ⅲ , ⅣV and Ⅱ level CHF group, IV and Ⅲ level CHF group, before and after CHF treatment, HCY and NT - proBNP levels were significant differences （P 〈 0. 01 ）. Hey and NT - proBNP posi-tive rates in CHF were higher significantly than these in control group（ P 〈 0. 05 ）. Conclusion：Detecting Serum Hcy and NT - proBNP levels contributes to diagnosis CHF and assess its severity, as well as evaluating its recent therapeutic effect.
出处
《内蒙古中医药》
2013年第22期97-98,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
