摘要
目的探讨痰热清配合常规治疗对慢性阻塞性肺疾病急性加重期(AECOPD)患者血清CRP及IL-10表达的影响,并观察临床疗效。方法将90例AECOPD患者随机分为治疗组与对照组,各45例,均予常规治疗,治疗组加用痰热清静滴,疗程为10 d。两组患者治疗前后测定血清CRP、IL-10含量。结果治疗组显效率较对照组明显提高,差异有显著性(P<0.05)。两组患者治疗后CRP表现出下降趋势。其中治疗组CRP下降更快;治疗组治疗后血清IL-10的含量明显低于对照组。结论在常规治疗的基础上联用痰热清治疗AECOPD能明显提高临床疗效;痰热清可阻止体内的炎症反应,对COPD急性加重期的治疗具有临床意义。
Objective To study the effect of Tanreqing combined with conventional treatment for serum CRP and IL-10 expression of patients with acute exacerbations of COPD （AECOPD）, and observe it＇s clinical effects. Methods A total of 90 patients with AECOPD were randomly divided into the treatment group and the control group, each group had 45 cases, two groups were given conventional treatment, and the treatment group were added Tanreqing intravenous drip,the course of treatment was 10 days. The serum CRP and IL-10 content of patients in two groups before and after treatment were determined. Results The efficiency of the treatment group was significantly higher than that of the control group, the difference was significant （P〈0.05）. The CRP of patients in two groups after treatment showed a downward trend, of all the CRP of the treatment group fell even faster; the IL-10 content in the treatment group after treatment was significantly lower than that in the control group. Conclusion Combined with Tanreqing on the basis of conventional treatment in treatment of AECOPD can obviously improve the clinical curative effect; Tanreqing can block the body＇s inflammatory response,and has clinical significance for treatment of acute exacerbations of COPD.
出处
《中国现代医生》
2013年第27期75-76,79,共3页
China Modern Doctor
