摘要
目的对伴发焦虑/抑郁的偏头痛患者血清C-反应蛋白(CRP)水平进行对照性研究。方法测定伴发焦虑/抑郁的偏头痛患者(n=46)血清CRP水平,并与不伴焦虑/抑郁的偏头痛患者进行对照(n=59);分析患者焦虑、抑郁程度与CRP水平的相关性。结果伴发焦虑/抑郁的偏头痛患者血清CRP水平(14.8±3.5mg/L)较不伴者(12.0±4.2mg/L)显著增高(t=3.641,P=0.0013),并与患者焦虑、抑郁自评量表评分正相关(r=0.307,0.441;P=0.035,0.0075)。结论伴发焦虑/抑郁的偏头痛患者血清C-反应蛋白水平相对较高,提示其可能存在更为显著的炎症激活状态。
Objective To evaluate the serum C--reactive protein level in migraine patients with anxiety and /or depression co- morbility. Methods Serum C--reactive protein level was measured in migraine patients with anxiety and /or depression eomorbili- ty （n： 46）and without comorbility （n = 59）. The correlation between severity of anxiety,depression and serum C--reactive protein level was analyzed. Results Serum C--reactive protein level was significantly higher in migraine patients with anxiety and/or de~ pression than those without. Serum C--reactive protein level was significantly correlated with the score of Self--rating Anxiety Scale （r= 0. 307 ,P= 0. 035）or Self-rating Depression Scale （r ： 0. 441, P = 0. 0075）in comorhility migraine patients. Conclusion There is a higher level of serum C--reactive protein in migraine patients with anxiety and /or depression compared to those with- out,which suggests a more active inflammatory status.
出处
《中国健康心理学杂志》
2013年第9期1309-1310,共2页
China Journal of Health Psychology
