摘要
目的:观察强脊方治疗肾虚督寒型强直性脊柱炎(AS)的临床疗效及安全性。方法:将78例肾虚督寒型强直性脊柱炎患者随机分为治疗组40例和对照组38例。治疗组采用强脊方治疗;对照组采用金乌骨通胶囊治疗。2组均治疗8周,治疗前后评价中医证候积分、Bath功能指数(BASF)I、疾病活动指数(BASDA)I、疼痛视觉模拟评分法(VAS)评分、病人总体评价(HAQ)、晨僵时间、指地距、胸廓活动度、枕壁距、Schober试验、血沉、C-反应蛋白及血尿常规、肝肾功能。结果:治疗后2组中医证候积分、HAQ、VAS评分、晨僵时间、BASDAI、BASFI、C-反应蛋白、Schober试验、指地距、枕壁距、胸廓活动度比较,差异均有显著性意义(P<0.05),治疗组改善优于对照组。总有效率治疗组为92.50%,对照组为76.32%,2组比较,差异有显著性意义(P<0.05)。结论:强脊方可有效改善肾虚督寒型强直性脊柱炎患者临床症状,临床疗效肯定。
Objective： To investigate the clinical efficacy and safety of Qiangji Decoction for the treatment of ankylosing spondylitis （AS） with kidney deficiency and governor vessel cold syndrome. Methods= Seventy-eight AS patients with the kidney deficiency and governor vessel cold syndrome were randomly divided into treatment group（n=40） and the control group （n=38）. The treatment group was treated with Qiangji Decoction, and the control group was given jinwu Gutong Capsules. One treatment course lasted eight weeks. Before and after treatment, we investigated Bath ankylosing spondylitis function index （BASFI）, Bath ankylosing spondylitis disease activity index （BASDAI）, visual analog scale （VAS） scores, patient＇s health assessment questionnaire（HAQ）, time of morning stiffness, finger to floor distance, chest expansion, occiput to wall distance, Schober＇s test, erythrocyte sedimentation rate （ESR）, C-reactive protein （CRP）, blood and urine routine examination, and liver and kidney function. Results： After treatment, traditional Chinese medical syndrome scores, HAQ, VAS scores, time of morning stiffness, BASDAI, BASFI, CRP, Schober＇s test, finger to floor distance, occiput to wall distance, and chest expansion were improved in both groups（P 〈 0.05 compared with those before treatment）, and the improvement was superior to that in the control group. The total effective rate was 92.50% in the treatment group and was 76.32% in the control group, the difference being significant（P 〈 0.05）. Conclusion= Qian#i Decoction shows certain effect for the treatment of AS patients with kidney deficiency and governor vessel cold syndrome.
出处
《新中医》
CAS
2013年第10期56-58,共3页
New Chinese Medicine
关键词
强直性脊柱炎(AS)
肾虚督寒型
强脊方
Ankylosing spondylitis,, Kidney deficiency and governor vessel cold syndrome
Qian^i Decoction
