摘要
目的探讨慢性乙型肝炎患者生活质量影响因素,旨在为采取针对性的干预措施改善患者的生活质量提供参考依据。方法笔者采用查阅大量参考文献制定的自编问卷、抑郁自评量表(SDS)、焦虑自评量表(SAS)、社会支持评定量表(SSRS)和汉化版简明健康调查表(SF-36量表),收集该院传染科2010年12月至2012年12月治疗的50例慢性乙型肝炎患者的临床资料,同时选择50例年龄与慢性乙型肝炎患者相匹配的健康体检者为对照组,应用SPSS19.0统计软件进行t检验和多元逐步回归分析找出慢性乙型肝炎患者生活质量和影响因素。结果慢性乙型肝炎患者的SF-36量表中各维度指标得分均明显低于健康体检者,差异有统计学意义(P<0.05),多元逐步回归分析发现文化程度、患者对慢性乙型肝炎疾病知识的了解程度、治疗依从性、主观支持分和社会支持评定量表总分与慢性乙型肝炎患者生活质量正相关,而典型临床症状和体征、焦虑抑郁情绪与慢性乙型肝炎患者生活质量负相关。结论慢性乙型肝炎患者的生活质量较低,其受很多因素影响。
Objective To explore the factors influencing the life quality of patients with chronic hepatitis B and to provide reference for targeted interventions to improve quality of life .Methods Self-constructed questionnaire , based on a large number of references ,Self-rating Depression Scale （SDS） ,Self-rating Anxiety Scale （SAS） ,Social Support Rating Scale （SSRS） and Chinese version of Concise Health Questionnaire （SF-36 scale） were used to collect clinical data of 50 cases of chronic hepatitis B patients treated in this hospital from Dec .2010 to Dec .2012 and 50 ca-ses of matched healthy subjects （control group） .All data were analyzed by multiple stepwise regression analysis and t test using SPSS19 .0 software to indentify factors influencing life quality of patients .Results Score of each dimen-sion in SF-36 scale of patient group was lower than control group （P〈0 .05） ,multiple stepwise regression analysis indicated that education ,knowledge of disease ,treatment compliance ,subjective support and social support rating scale were positively correlated ,but the typical signs and symptoms ,anxiety and depression were negatively correla-ted with life quality of patients ,.Conclusion Life quality of patients with chronic hepatitis B might be poor ,which could be influenced by many factors .
出处
《检验医学与临床》
CAS
2013年第17期2274-2276,共3页
Laboratory Medicine and Clinic
关键词
慢性乙型肝炎
生活质量
影响因素
chronic hepatitis B
life oualitw influencing factors
