摘要
目的比较年龄、血压、临床特征和持续时间(ABcD)评分、ABCD2评分、ABCD+低密度脂蛋白评分(ABCDL)和ABCD2+低密度脂蛋白评分(ABCD2L)4种评分在预测短暂性脑缺血发作(TIA)预后的价值。方法分别用4种评分法对在我院住院的235例老年TIA患者进行评分,观察患者2d、7d内脑梗死的发病率,用受试者工作特征曲线(ROC)比较4种评分方法的预测准确性;同时依据ABCD2L评分对患者进行危险分层,采用y。检验比较各组间脑梗死发病率的差异。结果预测TIA后2d卒中风险时,ABCD、ABCD2、ABCDL及ABCD2L评分的ROC曲线下面积分别为0.68(95%CI:0.59~0.76)、0.71(95%CJ:0.62~0.80)、0.73(95%Cj:0.65~0.82)、0.77(95%CI:0.69~0.84);预测TIA后7d脑梗死风险时,4种评分的ROC曲线下面积分别为0.73(95%Cf:0.66~0.81)、0.77(95%CI:0.70~0.84)、0.80(95oACI:0.74~0.87)、0.83(95%Cj:0.76~O.89)。进一步依据ABCD2L评分对患者进行危险分层,低危组(O~2分)28例、中危组(3~5分)143例和高危组(6~8分)45例,各组患者2d脑卒中发病率分别为0%(0例)、9.1%(13例)和32.8%(21例),7d脑卒中发病率分别为0%(0例)、11.9%(17例)和56.3%(36例),差异均有统计学意义(X2=26.15、58.87,均P〈0.05)。结论在预测老年患者TIA早期预后时,ABCD2评分优于ABCD评分,结合LDL可增加ABCD2评分的预测准确性。
Objective To compare the short term prognostic values between the four scores including ABCD, ABCD2, ABCD + low density lipoprotein (ABCD + LDL), ABCD2 + LDL after transient ischemic attack (TIA). Methods 235 TIA patients were evaluated according to ABCD score, ABCD2 score, ABCD + LDL score and ABCD2 + LDL score. The occurrence of cerebral infarction was observed at day 2 and 7. The predictive value was compared between the four scores by using receiver operating characteristic (ROC) curve. Patients were classified into 3 risk groups: low- risk group, moderate-risk group and high-risk group according to ABCD2 L score, and the stroke incidence was compared between the 3 groups by using X2 test. Results The area under ROC curves (AUCs) of ABCD,ABCD2,ABCDL and ABCD2L was 0.68 (95%CI: 0. 59-0. 76) , 0.71 (95%CI: 0.62 0.80), 0.73 (95%CI: 0.65-0.82) and 0.77 (95%CI: 0.69-0.84) in predicting the risk of cerebral infarction at day 2, and were 0. 73 (95%CI: O. 66-0. 81), 0. 77 (95~CI.. 0. 70-0. 84),0. 80 (95%CI.. 0.74-0.87) and 0.83 (95%CI: 0.76-0.89) in predicting the risk of cerebral infarction at day 7 respectively. Patients were divided into 3 groups: low-risk group (score 0-2) (n= 28), moderaterisk group (score 3-5) (n= 143) and high-risk group (score 6 8) (n= 45) according to ABCD2L score. There were significant differences in stroke incidence at day 2 and 7 between the 3 groups (0%, 9.1% vs. 32.8%, 0%, 11.9% vs. 56.3%, Z2=26.15, 58.87,both P〈0.05). Conclusions ABCD2 score is better than ABCD score in predicting the short term prognosis of transient ischemic attack. Combining ABCD2 score with LDL can significantly increase the predictivevalue of ABCD2 score.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2013年第10期1047-1050,共4页
Chinese Journal of Geriatrics