摘要
肝细胞癌(HCC)是全球最难治疗的恶性肿瘤之一,全球每年约有65万患者死于HCC。虽然其治疗手段繁多,但疗效仍不令人满意。目前,以经导管肝动脉化疗栓塞术(TACE)为代表的介入治疗已成为中晚期肝癌患者的主要治疗手段。介绍了经皮无水酒精注射、射频消融术、局部氩氦冷冻治疗、放射性粒子植入术等局部介入治疗的发展,以及与生物、基因治疗的联合应用,使综合介入治疗成为HCC最主要的非手术治疗模式。指出随着个体化、规范化的综合介入治疗手段的应用和推广,HCC的整体疗效将得到进一步提高。
Hepatocellular carcinoma （HCC） is one of the most refractory malignancies worldwide, and there are about 650 000 people who die of HCC each year around the world. Despite many treatment methods for HCC, the treatment outcome is still not satisfactory. At present, interventional treatment, represented by transcatheter arterial chemoembolization, has become the main treatment means for advanced HCC. It is mentioned that the development of local interventional therapies, such as percutaneous ethanol injection, radiofrequency ablation, local argon-helium cryoablation, and radioactive particle implantation, as well as the application of biotechnology and gene therapy, enables comprehensive interventional therapy to become the major non - surgical treatment mode for HCC. It is pointed out that with the wide appli-cation of individualized and standardized comprehensive interventional therapy, the overall treatment outcome of HCC will be further im-proved.
出处
《临床肝胆病杂志》
CAS
2013年第10期721-725,共5页
Journal of Clinical Hepatology
关键词
肝肿瘤
介入治疗
综合治疗
liver neoplasms
interventional treatment
comprehensive treatment
