摘要
目的 探讨阿莫西林克拉维酸钾治疗婴幼儿急性上呼吸道感染的临床疗效.方法 将128例急性上呼吸道感染患儿随机分为对照组（n=62）与观察组（n=66）,对照组给予阿莫西林口服,观察组给予阿莫西林克拉维酸钾口服,疗程7～～10d.比较2组临床疗效及不良反应发生率.结果 观察组治疗有效率为92.4％,显著高于对照组的71.0％,差异有统计学意义（P＜0.05）;观察组咽痛、发热及咽扁桃体充血缓解时间显著少于对照组（P＜0.05）;观察组与对照组不良反应发生率分别为6.1％和4.8％,差异无统计学意义（P＞0.05）.结论 与阿莫西林相比,阿莫西林克拉维酸钾治疗婴幼儿急性上呼吸道感染可显著提高临床疗效,改善症状,且不增加不良反应发生的概率.
Objective To explore the effect of amoxicillin and clavulanate potassium in the treatment of children acute upper respiratory tract infection. Methods A total of 128 children with acute upper respiratory tract infection were randomly divided into control group （ n = 62） and exper- iment group （n = 66）. The control group was given amoxicillin treatment, and the experiment group received amoxicillin and clavulanate potassium therapy. The course of treatment was 7 - 10 days. Clinical effect and adverse rates were compared between two groups. Results The effective- ness rate in the experiment group was much higher than that in the control group with significant difference （92.4% vs 71.0%, P〈 0.05）. The remission time of angina, fever and pharyngeal tonsils hyperemia in the experiment group were much earlier than those in the control group （ P 〈 0.05）. The adverse rates in the experiment group and the control group were 6.1% and 4.8 %, respectively （P 〉 0.05 ）. Conclusion Compared with amoxicillin, amoxicillin and clavulanate potassium for children with acute upper respiratory tract infection greatly improves the clinical effect and symptoms with less adverse reactions.
出处
《实用临床医药杂志》
CAS
2013年第19期107-108,共2页
Journal of Clinical Medicine in Practice
关键词
急性上呼吸道感染
阿莫西林克拉维酸钾
儿童
acute upper respiratory tract infection
amoxicillin and clavulanate potassium
children
