摘要
目的评价急性阑尾炎术后不同预防感染方案的成本与效果,从而促进本院临床治疗方案的合理选择。方法选择106例急性阑尾炎术后患者,按照给药方案分为A、B组,A组(n=69)给予注射用头孢替唑+甲硝唑氯化钠注射液,B组(n=37)给予头孢西丁注射,采用临床药物经济学的方法进行统计分析。结果 A、B组的显效率分别为89.86%、78.38%;平均总医疗成本分别为1063.1、999.1元;成本-效果比分别为11.81、12.74;敏感度分析显示:△C/△E=5.04,药品价格下降在12%范围内时,A组仍然为较经济的治疗方案。结论从药物经济学的角度,A方案为两种方案中用于急性阑尾炎术后预防感染的较优方案。
Objective To evaluate the cost and effectiveness of tow treatment programs for prevention affection of after appendectomy, and promote the rational choice of clinical treatment. Methods 106 cases of acute appendicitis postoperative patients were divided into group A,B,the patients in group A （n=69） were treated with ceftezole＋metronidazole injection,the patients in group B （n=37） were treated with cefoxitin,the two treatment programs were analyzed and evluated with pharmacoeconomics. Results The effective rate of group A and group B was 89.86% and 78.38% re- spectively;The costs were 1063.1 yuan and 999.1 yuan respectively;And the cost-effectiveness ratio was 11.81 and 12.74 respectively,sensitivity analysis showed that：AC/AE was 5.04,the fell of drug prices in the range of 12%,group A was more economical treatment than group B. Conclusion From the view of the pharmacoeconomics,group A pro- gram is better than that of group B program,which solution to prevent infection after surgery for acute appendicitis.
出处
《中国当代医药》
2013年第30期134-135,共2页
China Modern Medicine
关键词
急性阑尾炎
药物经济学
成本-效果分析
Acute appendicitis
Pharmacoecnomics
Cost-effectiveness analysis
