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腰丛-坐骨神经阻滞下行膝关节置换术中辅助右美托咪啶麻醉效果的观察 被引量:6

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摘要 目的:观察腰丛-坐骨神经阻滞下膝关节置换术中辅助右美托咪啶的麻醉效果.方法:40例择期膝关节置换术者随机分两组(n=20):腰丛-坐骨神经阻滞+右美托咪啶组(D组)和腰丛-坐骨神经阻滞+咪唑安定组(M组).两组均先静脉推注舒芬太尼0.5 μg/kg,D组经微量输液泵以1 μg/(kg·h)的速度推注右美托咪啶10 min,M组缓慢静脉推注咪唑安定0.04 mg/kg后,患者神经刺激仪引导下行腰丛-坐骨神经阻滞,效果满意后20 min,D组以0.5 μg/(kg·h)右美托咪啶维持麻醉至手术结束.记录患者入室(T0)、麻醉后手术开始前(T1)、切皮后10 min(T2)、置换关节时(T3)及手术结束时(T4)的平均动脉压(mean artery pressure,MAP)、心率(heart rate,HR)、脉搏血氧饱和度(pulse oxygen saturation,SpO2)、Ramsay镇静评分及围手术期的不良反应.结果:两组患者T0时MAP、HR差异无统计学意义(P〉0.05);D组在手术前后MAP、HR差异无统计学意义(P〉0.05),M组MAP、HR在手术后较之手术前均显著升高(P〈0.05);D组在T2、T3时MAP、HR显著低于M组(P〈0.05).两组各时间段SpO2差异无统计学意义(P〉0.05),Ramsay 镇静评分均达到2~4分.D组术中体动、高血压、心动过速、呼吸抑制及寒颤的发生率均显著低于M组(P〈0.05).结论:腰丛-坐骨神经阻滞下膝关节置换术中辅助右美托咪啶麻醉安全可靠,效果满意.
出处 《南通大学学报(医学版)》 2013年第5期412-414,共3页 Journal of Nantong University(Medical sciences)
基金 南通市应用研究计划资助项目(2013BK062) 南通大学杏林学院科研基金资助项目(2012K133)
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参考文献7

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