摘要
目的 评价单位设计临床容积调强弧形治疗（VMAT）计划质量差异,建立VMAT计划设计通用模板.方法 5家肿瘤中心分别提供1例病例作为测试例,CT及轮廓经确认后导入计划系统.各中心使用相同处方和剂量限制要求进行计划设计,具体设计策略自行决定.每个测试例包含5例各中心完成的计划和1例使用通模板完成的计划.采用计划质量整体评分法评估计划质量,使用机器跳数和治疗时间评估计划执行效率.结果 鼻咽癌病例没有计划可以严格满足所有剂量目标,3例计划虽然无法满足所有目标但可达到临床接受水平,另3例计划无法接受.食管癌病例6例计划均可达到临床接受水平.肺癌病例4例计划达到临床接受的水平,2例计划无法接受.前列腺癌病例4例计划严格满足所有剂量目标,1例计划达到临床接受水平,1例计划无法接受.肝癌病例3例计划严格满足所有剂量目标；3例计划达到临床接受水平.在执行效率方面,各计划控制点数80～ 160个,治疗时间3～7 min,机器跳数350～900 MU.结论 大部分计划的质量和执行效率可以达到临床要求,各中心设计基于Monaco系统的VMAT计划模板及基准数据库的质量也达到了预期.
Objective To evaluate the quality of volumetric modulated arc therapy （VMAT） plans among the sites and establish the common template for VMAT plan.Methods One test case was provided by each of five sites accordingly,and the CT with contours was send to the TPS after approved.All participants were asked to wake the VMAT plans for these test cases with uniform dose prescription and follow the planning strategy of their choice.Each test case includes five plans designed by the participants and one plan generated with the template.The quality score was used to evaluate the plan quality,and the MU with treatment time was used for execution efficiency.Results For NPC case,no plan was able to fulfill all dose objectives strictly; three plans failed some of the objectives but were still considered to be clinically acceptable;the other three plans were not able to reach the objectives.For Esophagus case,all six plans were considered to be clinically acceptable.For lung case,four plans were considered to be clinically acceptable;two plans were not able to reach the objectives.For Prostate case,four plans were able to fulfill all dose objectives strictly;one plan was still considered to be clinically acceptable;one plan was not able to reach the objectives.For Liver case,three plans were able to fulfill all dose objectives strictly;three plans were considered to be clinically acceptable.About the execution efficiency,treatment duration was 3-7 min,amount of MU was 350-900 MU,amount of control points was 80-160.Conclusions The presented planning studies showed that quality and execution efficiency for most plan have achieved the clinical requirements; the quality of VMAT plan＇s template and benchmark database also meet the expectation.
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
2013年第6期473-477,共5页
Chinese Journal of Radiation Oncology
关键词
容积调强弧形治疗
多中心计划比较
计划模板
Keywords：Volumetric modulated arc therapy
Muti-center plan comparison
Plan template
