1JACKMAN D M,JOHNSON B E. Small - cell lung cancer[ J].Lancet, 2005, 366(9494) : 1385 -1396.
2D'ANGELO S P, PIETANZA M C. The molecular pathogenesis ofsmall cell lung cancer[ J]. Cancer Biol Ther, 2010, 10(1) : 1 -10.
3EGGER G,LIANG G, APARICIO A,et al. Epigenetics in hu-man disease and prospects for epigenetic therapy [ J ]. Nature,2004, 429(6990) ; 457 -463.
4FEINBERG A P,TYCKO B. The history of cancer epigenetics[J]. Nat Rev Cancer, 2004,4(2) : 143 -153.
5LAIRD P W. The power and the promise of DNA methylationmarkers[J]. Nat Rev Cancer, 2003,3(4) : 253 -266.
6GRANDORI C, EISENMAN R N. Myc target genes[ J]. TrendsBiochem Sci, 1997, 22(5) : 177-181.
7KRYSTAL G,BIRRER M,WAY J, et al. Multiple mechanismsfor transcriptional regulation of the myc gene family in small - celllung cancer[J]. Mol Cell Biol, 1988 , 8(8) : 3373 -3381.
9LIN R K, HSUB H S, CHANG J W, et al. Alteration of DNAmethyltransferases contributes to 5'CpG methylation and poor prog-nosis in lung cancer [ J ]. Lung Cancer, 2007 , 55 ( 2 ) : 205 -213.
10HARRIS C C. p53 tumor suppressor gene: from the basic researchlaboratory to the clinic-an abridged historical perspective[ J].Carcinogenesis, 1996, 17(6) : 1187 -1198.
