摘要
目的探讨血液病患者输注血小板的临床疗效及其无效输注的影响因素。方法回顾性分析我院收治有血小板输注(platelet transfusion,PT)史血液病患者76例,共输注血小板287次,其中有效输注174例次,无效输注113例次。Logistic逻辑回归分析比较影响患者PT效果的相关因素。结果单因素分析显示反复PT(χ2=39.26,P<0.01)、感染(χ2=8.62,P<0.01)、脾肿大(χ2=29.53,P<0.01)和活动出血(χ2=4.82,P<0.05)与无效PT有关。Logistic回归分析显示PT≥3次(OR=3.42,P=0.001),脾肿大(OR=3.01,P=0.002)是导致无效PT的独立因素。结论反复输注血小板的脾肿大患者发生无效PT的风险相对较高。
Objective To evaluate the invalid risk factors for blood platelet transfusion in patients with clinical effica- cy. Methods A total of 76 cases of blood diseases patients with 287 times platelet transfusion were retrospectively ana- lyzed. In these 76 subjects, there were 174 times with valid platelet transfusion and 113 times with invalid platelet transfusion. The risk factors for the invalid platelet transfusion were analyzed by logistic regression. Results Single fac- tors analysis by chi-square showed that the multiple platelet transfusion （X2=39.26,P〈0.01）, infection （xZ=8.62,P〈 0.01 ）, enlarged spleen （X2=29.53 ,P〈0.01） and active hormoge （X2=4.82,P〈0.05） were associated with the invalid platelet transfusion. Logistic regression demonstrated that platelet transfusion ≥3 times （OR=3.42,P=0.001） and enlarged spleen （OR =3.01 ,P=0.002） were the independent risk factors for invalid platelet transfusion. Conclusion Patients with en- larged spleen and more than 3 times platelet transfusion have the relatively higher risks of invalid platelet transfusion. [Key words] Blood disease; Platelet transfusion; Risk factors
出处
《中国现代医生》
2013年第31期40-42,共3页
China Modern Doctor
基金
国家中医药管理局中医药行业科研专项立项计划(201107001-14)
关键词
血液病
血小板输注
危险因素
Blood disease
Platelet transfusion
Risk factors
