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血清CA199、CA242及CEA联合检测对胰腺癌的诊断价值 被引量:14

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摘要 目的:探讨糖抗原199(CA199)、糖抗原242(CA242)、癌胚抗原(CEA)联合检测对胰腺癌的诊断价值。方法:应用化学发光法及酶联免疫法检测56例胰腺癌患者与36例健康体检者血清中CA199、CA242、CEA浓度。结果:胰腺癌患者血清CA199、CA242及CEA浓度均比正常对照组升高(均P<0.05);有淋巴结转移患者血清CA199、CA242及CEA浓度均比无淋巴结转移患者升高(均P<0.05);CA199、CA242及CEA诊断胰腺癌敏感性分别为82.1%、71.4%、46.4%,特异性分别为73.2%、75.0%、71.4%;CA199、CA242及CEA联合检测诊断胰腺癌敏感性达94.6%(53/56),特异性达89.3%(50/56)。结论:血清CA199、CA242及CEA联合检测对胰腺癌的诊断具有重要的临床价值,可明显提高诊断胰腺癌的敏感性和特异性,具有良好的临床应用价值。
出处 《广西医科大学学报》 CAS 2013年第5期725-726,共2页 Journal of Guangxi Medical University
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