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膀胱部分切除术治疗老年肌层浸润性膀胱癌的疗效 被引量:14

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摘要 目的 分析膀胱部分切除术(PC)治疗老年肌层浸润性膀胱癌(MIBC)患者的临床疗效.方法 回顾性分析43例经PC后确诊为肌层浸润性膀胱癌(T2N0M0)的老年患者临床资料,术后均给予吉西他滨和顺铂(GC)方案化疗加膀胱灌注治疗.结果 患者均获得随访,随访6~54个月,平均(26±3.4)个月,其中38例(88.4%)无复发及转移,5例(11.6%)在术后13个月内复发,复发患者2例行膀胱全切,其余行经尿道膀胱肿瘤切除术(TUR-BT),无死亡病例,无明显并发症.结论 PC治疗老年MIBC可以达到一定的临床疗效,术后配合化疗及膀胱内灌注治疗,能有效减少膀胱肿瘤复发.
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第22期5581-5582,共2页 Chinese Journal of Gerontology
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参考文献7

  • 1Ramani VA, Maddineni SB, Grey BR, et al. Differential complication rates following radical cystectomy in the irradiated and nonirradiated pelvis[J]. Eur Urol,2010;57(6) :1058-63.
  • 2Solsona E, Clment MA, Iborra I, et al. Bladder preservation in selected patients with muscIe-invasive bladder cancer by complete transurethral resection of the bladder plus systemic chemotherapy:long-term follow-up of a phase 2 nonrandomized comparative trial with radical cystectomy [J]. Eur Urol,2009 ;55:911-9.
  • 3Heney NM, Kaufman DS, Shiplcy WU. Surgery : selective bladder-preser- ving therapy for muscle-invasive cancer[J]. Nat Rev Clin 0ncol,2009 ;6 (4) :193-4.
  • 4侯建国,杨波,孙颖浩,万蓬.浸润性膀胱癌患者的保留膀胱综合治疗[J].临床泌尿外科杂志,2004,19(10):619-620. 被引量:12
  • 5Rosenberg JE, Carroll PR, Small EJ. Update on chemotherapy for ad- vanced bladder cancer[J] J Urol,2005 ;174( 1 ) :14-20.
  • 6Yucel M, Hatipoglu NK, Atakanli C,et aL Is repeat transrurethral resec- tion effective and necessary in patients with T1 bladder carcinoma[ J]. J Urol Int ,2010 ;85 (3) :276-80.
  • 7Kauffman D, Raghavan D, Carducci M, et al. Phase ]] trial of gemcit- abine plus cisplatin in patients with metastatic urothelial cancer[ J ]. Clin Oncol, 2000 ; 18 : 1921-7.

二级参考文献4

  • 1Dunst J , Rodel C , Zietman A , et al. Bladder preservation in muscle-invasive bladder cancer by conservative surgery and radiochemotherapy. Semin surg oncol,2001, 21: 24-32.
  • 2Kaufman D S, Winter K A, Shipley W U, et al. The initial results in muscle- invading bladder cancer of RT0G 95-06: phase Ⅰ/Ⅱ trial of transurethral surgery plus radiation therapy with concurrent cisplatin and 5-fluorouracil followed by selective bladder preservation or cystectomy depending on the initial response. Oncologist, 2000, 5: 471-476.
  • 3Shipley W U, Kaufman D S, Lane S C, et al . Selective bladder preservation by combined modality protocol treatment: long-term outcomes of 190 patients with invasive bladder cancer. Urology, 2002, 60: 62-67.
  • 4Kachnic L A, Kaufman D S, Griffin P P, et al. Bladder preservation by combined modality therapy for invasive bladder cancer. J Clin Oncol, 1997, 15: 1022-1029.

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