摘要
目的研究2011年中国在校学生肺结核报告发病率及疫情特征。方法采用数据挖掘方法,由国家疾病监测信息报告管理系统获得全人群、学生肺结核报告发病例数数据,根据中国统计年鉴统计在校学生人数,两者结合共同计算全人群、学生肺结核报告发病率。由结核病管理信息系统获取全人群、学生登记肺结核患者人口学特征、诊断分类及预后数据。由国家突发公共卫生事件管理信息系统获取结核病突发事件报告信息。采用上述数据对比分析在校学生肺结核疫情特征。结果2011年全人群肺结核报告发病率为71.09/10万(953 275/1 340 909 996),在校学生肺结核报告发病率为20.16/10万(41 608/206 339 584)。山东省在校学生肺结核报告发病率最低,为10.54/10万(1508/14 300 995),西藏的在校学生肺结核报告发病率最高,为66.24/10万(350/528 389)。2011年登记学生患者的涂阳比率为30.59%(12 193/39 853),低于全人群患者涂阳比率的46.82%(423 830/905 344),差异有统计学意义(χ2=3542.85,P<0.01)。学生初治涂阳患者2个月末痰菌转阴率(97.37%,11 310/11 616)及治愈率(95.56%,11 278/11 802)均高于全人群患者(93.83%,353 729/377 005;93.98%,353 238/375 859),差异均有统计学意义(χ2值分别为247.70和50.79,P值均<0.01)。结论2011年中国在校学生肺结核报告发病率约为全人群报告发病率的1/3,学生登记涂阳肺结核患者比率低,而学生初治涂阳患者治愈率较高,学校结核病控制仍需进一步加强。
Objective To explore the reported incidence and epidemic features of pulmonary tuberculosis （PTB） in students in China. Methods We got numbers of reported PTB patients （students and whole population） data from Chinese Infectious Disease Report Information System and abstracted total numbers of students in school using data from China Statistical yearbook, then used them to calculated incidence of reported PTB patients （students and whole population）. Besides, we got data of demographic, incidence and prognosis features of registered PTB patients （students and whole population） from Chinese Tuberculosis Information Management System, and PTB emergencies reports from Chinese Public Health Emergencies Information Management System. Together we used data mining methods to analyze the epidemic features of PTB patients among school students in 2011. Results The reported PTB incidence in students was 20.16/100 000 （41 608/206 339 584） in 2011, while in whole population the incidence was 71.09/100 000 （953 275/1 340 909 996）. The highest and lowest reported PTB incidences at provincial level in 2011 were 66.24/100 000 （Tibet, 350/528 389） and 10.54/100 000 （Shandong, 1508/14 300 995）. In 2011, 30.59%（12 193/39 853） registered PTB patients in student were smear positive, the proportion was higher than that in all PTB patients （46.82%, 423 830/905 344） （χ2=3542.85, P〈0.01）.The primary smear-positive patients in students got higher sputum negative conversion rate after 2 months treatment （97.37%, 11 310/11 616） and cure rate （95.56%,11 278/11 802） than all PTB patients （93.83%, 353 729/377 005; 93.98%, 353 238/375 859）（χ2=247.70/50.79, All P〈0.01）. Conclusion In China, the reported incidence of PTB in students is approximately 1/3 of all PTB patients, and the proportion of smear positive cases is lower than whole TB cases, while the cure rate is higher than whole TB cases. However, some provinces and prefectures still need to enhance TB control in students, detect and report public health emergencies induced by TB in school more timely.
出处
《中国防痨杂志》
CAS
2013年第11期871-875,共5页
Chinese Journal of Antituberculosis
基金
全球基金结核病实施性研究项目(12-011)
关键词
结核
肺
流行病学
发病率
学生
Tuberculosis, pulmonary/epidemiology
Incidence
Students
