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依折麦布联合阿托伐他汀治疗老年不稳定型心绞痛疗效观察 被引量:4

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摘要 目的观察依折麦布联合阿托伐他汀治疗老年不稳定型心绞痛的疗效及安全性。方法 98例老年不稳定型心绞痛患者随机分为2组,每组49例,观察组应用依折麦布10 mg/d联合阿托伐他汀10 mg/d,对照组单用阿托伐他汀20 mg/d,疗程2周。观察治疗2周后患者的血脂、HsCRP、肝肾功、CK的变化及心血管事件及不良反应的发生率。结果 2周后两组患者总胆固醇、低密度胆固醇、HsCRP均较前下降,但观察组下降较对照组更显著(P<0.05)。且观察组不良心血管事件(再发心绞痛、心肌梗死)发生率明显低于对照组(P<0.05)。结论依折麦布联合阿托伐他汀治疗不稳定型心绞痛比单用阿托伐他汀更显著降低胆固醇水平,减少心血管事件,具有良好的安全性。
作者 刘富群
出处 《中国现代药物应用》 2013年第22期82-84,共3页 Chinese Journal of Modern Drug Application
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参考文献7

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