摘要
目的:探讨血清和胸水中癌胚抗原(CEA)、糖类抗原125(CA125)、神经原特异性烯醇化酶(NSE)的检测对肺癌的诊断意义。方法:采用ACCESS2全自动化学发光仪对83例肺癌患者及58例正常对照组进行CEA、CA125、NSE测定。结果:肺癌组胸水各指标与同组血清水平比较差异有显著性(P<0.01),与正常对照组血清和胸水水平比较也有差异(P<0.01)。胸水中三项联合检测诊断肺癌的敏感度高达95.2%,血清中三项联合检测诊断肺癌的敏感度为89.2%。结论:联合检测血清和胸水中CEA、CA125、NSE对肺癌的诊断具有重要意义。
Objective：To explore the diagnostic significance of CEA, CA125, NSE in lung cancer serum and hy- drothorax. Methods ：The level of CEA, CA125, NSE in 83 lung cancers and 58 healthy people were determined using ACCESS2 automatic immue chemiluminescence system assay. Results：There was significant difference in lung cancer group of the level of CEA, CA125, NSE between serum and hydrothorax （ P 〈 0.01 ） , and there was difference of the healthy group both in serum and in hydrothorax （ P 〈 0.01 ）. The sensitivity of the three markers combined to diagnose lung cancer in hydrothorax was 95.2% ,and it was 89.2% in serum. Conclusion：There is import diagnostic signifi- cance of the combined detection of CEA, CA125, NSE in lung cancer patients＇s serum and hydrothorax.
出处
《现代肿瘤医学》
CAS
2013年第12期2713-2714,共2页
Journal of Modern Oncology
