摘要
目的:探讨中药联合重组白介素-Ⅱ治疗难治性特发性血小板减少性紫癜的临床疗效。方法:将52例难治性特发性血小板减少性紫癜患者随机分成两组,治疗组26例给予重组人白介素-Ⅱ(巨和粒)治疗,皮下注射,每天1次,每月连用14 d,疗程2个月,并口服中药汤剂(由黄芪、生地黄、仙鹤草、水牛角、牡丹皮、紫珠草等组成),每日1剂,早晚分服;对照组26例只给予重组人白介素-Ⅱ(巨和粒)治疗。疗程为2个月。结果:治疗组有效率为88.5%,对照组有效率为65.4%,两组比较差异有统计学意义(P<0.05)。结论:中药联合重组白介素-Ⅱ对难治性特发性血小板减少性紫癜有显著疗效。
Objective ： To explore the clinical curative effect of Chinese medicine combined with recombinant interleukin- Ⅱ in treating re- fractory idiopathic thrombocytopenic purpura. Methods ：52 cases of renal anemia refractory idiopathic thrombocytopenic purpura patients were randomly divided into two groups, the treatment group of 26 cases was given recombinant human interleukin- Ⅱ （ Juheli）, subcuta- neous injection, 1 time a day, continuous use 2 weeks per month, and 2 months as a course of treatment, and oral Chinese medicine de- coction （composition：radix astragali, radix rehmanniae, herba agrimoniae, buffalo horn, cortex moutan, callicarpa macrophylla vahl, etc）, daily 1 agent, taking medicine in the morning and evening;The control group of 26 cases was given only recombinant human inter- leukin- Ⅱ（Juheli）. 2 months as a course of treatment for the two groups. Results ： The effective rate of treatment group was 88.5 %, and the control group was 65.4% ,comparison of the two groups showed that the difference was statistically significant（P 〈 0.05）. Conclu- sion：Chinese medicine combined with recombinant interleukin-II in treating refractory idiopathic thrombocytopenic purpura has signifi- cant curative effect.
出处
《中医学报》
CAS
2013年第12期1890-1892,共3页
Acta Chinese Medicine
基金
江苏省中医药管理局资金项目(编号:SC200972)
关键词
血小板减少性紫癜
重组白介素-Ⅱ
中药
idiopathic thrombocytopenic purpura
recombinant interleukin-Ⅱ
Chinese medicine
