摘要
目的 探究莫沙必利和帕罗西汀结合对功能性消化不良进行治疗的临床效果.方法 选取在浙江省舟山医院消化内科2012年1月～2013年6月收治的150例功能性消化不良患者作为对象.将患者随机分为两组,每组各75例.实验组用莫沙必利和帕罗西汀进行治疗,对照组患者用莫沙必利进行治疗,对两组患者进行治疗效果、汉密尔顿抑郁量表（HAMD）以及汉密尔顿焦虑量表（HAMA）的评定.结果 实验组患者的治疗总有效率为94.67％,高于对照组的78.67％,差异有统计学意义（P＜0.05）.治疗后实验组HAMA得分为（8.86±3.15）分,对照组为（16.82±3.24）分;治疗后实验组HAMD得分为（7.18±2.84）分,对照组为（14.47±3.36）分;两组比较差异均有统计学意义（均P＜0.05）.结论 莫沙必利和帕罗西汀结合治疗功能性消化不良患者总有效率高,且复发率低,值得临床推广.
Objective To explore the clinical effect of Mosapride combined with Paroxetine in the treatment of functional dyspepsia.Methods 150 cases of patients with functional dyspepsia admitted to Zhoushan Hospital of Zhejiang Province from January 2012 to June 2013 were chosen as objects.The patients were randomly divided into two groups,with 75 cases in each group,the experiment group was treated with Mosapride and Paroxetine,the control group was treated with Mosapride.The treatment effect,Hamilton depression scale （HAMD） and Hamilton anxiety scores （HAMA） of two groups were assessed.Results The total effective rate of experiment group was 94.67％,higher than the 78.67％ of control group,the difference between the two groups was statistically significant （P ＜ 0.05）.After treatment,the HAMA score of experiment group was （8.86±3.15） points,which of control group was （16.82±3.24） points; HAMD score of experimental group was （7.18±2.84） points,which of control group was （14.47±3.36） points; the differences between the two groups were statistically significant （P ＜0.05）.Conclusion Mosapride combined with Paroxetine in the treatment of patients with functional dyspepsia has a high total effective rate,and the recurrence rate is low,which is worthy of clinical promotion.
出处
《中国医药导报》
CAS
2013年第32期89-91,共3页
China Medical Herald
