摘要
目的探讨西洋参和黄芪提取物合用对小鼠免疫功能的影响。方法昆明种小鼠随机分为阴性对照组、西洋参黄芪提取物低剂量组(53.3 mg/kg体重)、中剂量组(533 mg/kg体重)、高剂量组(1 600 mg/kg体重),阴性对照组给予食用植物油,连续灌胃给药30 d后,对小鼠进行细胞免疫指标、体液免疫指标、巨噬细胞吞噬功能及NK细胞活性测定。结果中、高剂量组小鼠足跖肿胀度值明显高于阴性对照组;中、高剂量组小鼠脾淋巴细胞增殖能力明显增高明显高于阴性对照组;中、高剂量组小鼠碳廓清能力明显高于阴性对照组;高剂量组小鼠抗体生成细胞数明显高于阴性对照组。结论西洋参黄芪提取物能够增强小鼠细胞免疫和单核-巨噬细胞功能,对小鼠具有提高免疫力作用。
Objective To study the effects of Panax quinquefolium together with Astrgalus on the immune function in mice. Methods Mice were randomly divided into control group,low dose group（ 53. 3 mg / kgBW）,middle dose group（ 533 mg/kgBW） and high dose group（ 1 600 mg/kgBW）. The control group was given edible oil. The data of cellular immunity,humoral immunity,macrophage phagocytosis function and the activities of NK cells were examined and collected after 30 days. Results The toe swelling value of middle and high dose groups were significant higher than that of control group. The proliferation of T cells of middle and high dose groups were significant higher than that of control group. The index of macrophages for carbon clearance of middle and high dose groups were significant higher than that of control group. The number of antibody-produing cells in spleen of high dose group was significant higher than that of control group. Conclusion The results indicated that Panax quinquefolium combined with Astrgalus could enhance the immune function in mice.
出处
《首都公共卫生》
2013年第6期248-251,共4页
Capital Journal of Public Health
关键词
西洋参
黄芪
免疫功能
小鼠
Panax quinquefolium
Astrgalus
Immune function
Mice
