摘要
目的:观察常规西药治疗基础上加用肾康注射液及血栓通注射液治疗早期糖尿病肾病的临床疗效。方法:选取80例早期糖尿病肾病患者,以数字表格法分为治疗组与对照组各40例,对照组常规治疗,治疗组在常规治疗基础上加用肾康注射液、血栓通注射液静脉滴注,每天1次,疗程2周,观察治疗前后血尿素氮(BUN)、肌酐(SCr)、尿微量白蛋白(MA)、β2-微球蛋白(β2-MG)变化及中医证候评分变化。结果:治疗前2组中医证候评分比较,差异无显著性意义(P>0.05),2组治疗后均较治疗前下降,与治疗前比较,差异有显著性意义(P<0.05),治疗组低于对照组,组间比较差异有显著性意义(P<0.05)。2组患者治疗前BUN、SCr、MA、β2-MG比较,差异均无显著性意义(P>0.05),2组治疗后BUN、SCr、MA指标均较治疗前下降,与治疗前比较,差异均有显著性意义(P<0.05),β2-MG治疗组治疗后较治疗前下降,与治疗前比较,差异有显著性意义(P<0.05),对照组治疗前后比较,差异无显著性意义(P>0.05),治疗后BUN、SCr、MA、β2-MG组间比较,治疗组均较对照组为低(P<0.05)。结论:肾康注射液联合血栓通注射液治疗早期糖尿病肾病能明显改善肾功能,疗效较好,值得推广。
Objective： To observe the combination of Shenkang injection and Xueshuantong injection on the basis of conventional western medicine in treating early diabetic nephropathy. Methods： Eighty patients with early diabetic nephropathy were divided into treatment group and control group by the random number, 40 cases in each group. The control group was given conventional western medical treatment, and the treatment group was given intravenous injection of Shenkang injection and Xueshuantong injection once daily on the basis of conventional treatment. The treatment course lasted 2 weeks. Before and after treatment, the changes of blood urea nitrogen （BUN）, serum creatinine （SCr）, urinary micro-amount albumin（MA）, and beta 2-microglobulin（β2-MG） as well as the scores of traditional Chinese medical symptoms were observed. Results： The scores of traditional Chinese medical symptoms were similar in both group before treatment（P 〉 0.05）, then were decreased after treatment（P〈 0.05）, and were lower in the treatment group than those in the control group（P〈 0.05）. The differences of BUN, SCr, MA and β2-MG were insignificant in both groups before treatment（P〉0.05）. After treatment, BUN, SCr, and MA were decreased in both groups（P〈0.05）, and β2-MG was decreased in the treatment group（P〈 0.05） but did not change much in the control group（P 〉 0.05）. The levels of BUN, SCr, MA and β2-MG were lower in the treatment group in comparison with the control group after treatment（P 〈 0.05）. Conclusion. Shenkang injection and Xueshuantong injection on the basis of conventional western medicine is effective in treating early diabetic nephropathy through significantly improving the renal function.
出处
《新中医》
CAS
2014年第1期112-114,共3页
New Chinese Medicine
关键词
糖尿病肾病
早期
肾康注射液
血栓通注射液
Diabetic nephropathy., Early stage
Shenkang injection
Xueshuantong injection
