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直接PCI术前负荷剂量阿托伐他汀对急性心肌梗死患者近期预后的影响分析 被引量：4

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摘要 目的分析直接经皮冠状动脉介入(PCI)治疗术前负荷剂量阿托伐他汀对急性心肌梗死患者近期预后的影响。方法根据是否直接行PCI术将85例未使用他汀类药物的ST段抬高型心肌梗死患者分组,对照组术前无他汀类药物预处理,强化组术前予阿托伐他汀,观察术后血流灌注情况和术后30 d内心血管不良事件发生情况。结果强化组TIMI血流3级发生率86.05%高于对照组的66.67%,CTFC低于对照组,TMPG高于对照组,P<0.05或P<0.01;强化组心血管不良事件发生率6.98%与对照组9.52%比较,P>0.05。结论直接行PCI术前强化他汀治疗能够通过稳定血管内斑块、减少远端血栓和微血管痉挛等机制改善冠脉血流和心肌灌注,且不增加心血管不良事件发生率。
作者 林森 韩培立 周朝元
机构地区 新乡医学院第一附属医院心血管外科
出处 《中国现代药物应用》 2014年第1期174-175,共2页 Chinese Journal of Modern Drug Application
关键词 经皮冠状动脉介入术 阿托伐他汀 急性心肌梗死 TIMI血流分级
分类号 R542.22 [医药卫生—心血管疾病]
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中国现代药物应用
2014年 第1期

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