摘要
目的：调查老年前列腺癌患者抑郁症状的发生状况并探讨相关因素。方法通过老年抑郁量表（GDS）、社会支持量表（SSRS）评估145例老年前列腺癌患者（平均72.9±6.7岁）的抑郁症状及社会支持状况，并调查社会人口学及临床资料，并运用多元回归分析及Logistic回归分析方法分析前列腺癌抑郁症状的影响因素。结果前列腺癌患者GDS得分为（8.69±2.13）分，其中34例（23.5%）患者存在明显的抑郁症状。Logistic回归分析表明教育程度、癌痛、糖尿病、高血压、外科去势是老年前列腺癌患者抑郁症状的重要影响因素。前列腺癌患者社会支持总分为（33.86±7.10）分，客观支持得分为（8.25±2.13）分，主观支持得分为（18.54±3.67）分，支持利用度得分为（7.06±2.12）分，多元回归分析显示社会支持总分、主观支持得分和睾酮是前列腺癌患者抑郁症状重要影响因素。结论抑郁症状是前列腺癌患者常见的情绪障碍，临床医生在临床工作中应注意筛查，其影响因素有教育程度、癌痛、高血压、糖尿病、外科去势、睾酮及社会支持。应加强前列腺癌患者的心理干预及社会支持以减少抑郁症状，提高老年前列腺癌患者的生活质量。
Objective To investigate the status of depressive symptom among elderly prostate cancer and explore its related factors.Methods The Geriatric Depression Scale（GDS）and Social Support Rating Scale were used to evaluate depression and social support in 145 prostate cancer [age （72.9±6.7 ） years ]. Meanwhile, the demographic and clinical data were also investigated. The impact factors of depression for prostate cancer were analyzed by stepwise logistic regression and multiple linear regression.Results The average GDS scores of all subjects were 8.69±2.13, 34 （23.5%）cases suffered from depressive symptom.The multi-factor non-condition logistic regression analysis showed that education status,cancer pain,diabetes mellitus,hypertension and surgical castration were important factors for independently prediction of depressive symptom in prostate cancer patients. The average SSRS scores of all subjects were 33.86±7.10, the average scores of objective support were 8.25±2.13, the average scores of subjective support were 18.54±3.67, the average scores of the utility
of social support were 7.06±2.12. The multiple linear regression analysis showed the total score of social support, score of subjective support and testosterone were important related factors for depression symptom of prostate cancer patients. Conclusion Depression is common in prostate cancer patients, More attention should be paid to depression screening in clinical practice.The impact factors of depressive symptom among prostate cancer include education status, cancer pain, diabetes mellitus, hypertension, castration, testosterone and social support. Psychological counseling should be further given to prostate cancer patients to reduce depressive symptom and improve their quality of life.
出处
《中国男科学杂志》
CAS
CSCD
北大核心
2013年第10期25-29,共5页
Chinese Journal of Andrology
基金
安徽医科大学校科学研究基金资助项目（No.2012xkj082）：安徽省科技计划项目资助（No.08020303067）
关键词
前列腺肿瘤
抑郁
社会支持
prostatic neoplasms
depression
social Support
