摘要
目的:为提高甲硝唑的临床合理用药水平提供参考。方法:查阅2012年7-12月某院使用过甲硝唑的住院患者的病历资料,统计其联合用药情况并进行分析。结果:共546例患者使用过甲硝唑,以预防为目的的用药占47.81%(261例),以治疗为目的的用药占52.19%(285例)。有97.80%(534例)的患者使用甲硝唑时联用了其他抗菌药物,共联合用药599次,其中不合理联用占20.70%(124次)。使用次数最多的联用方案为甲硝唑+头孢呋辛,不合理联合用药次数最多的方案为甲硝唑+头孢哌酮/舒巴坦。结论:甲硝唑的不合理联合用药在临床中比较常见,亟需引起临床工作者足够的关注,进一步规范抗厌氧菌药物的合理应用。
OBJECTIVE： To provide reference for the improvement of rational use of metronidazole in the clinic. METHODS： Medical records of inpatients receiving metronidazole during Jul.-Dec. in 2012 were retrospective reviewed and information about drug combination was extracted and analyzed statistically. RESULTS： 546 patients were treated with metronidazole, prophylactic drug use accounted for 47.81% （261 cases） and drug treatment accounted of 52.19% （285 cases）. In most of patients, metronidazole was prescribed combining with other drugs, which accounted for 97.80% （534 cases）. The total number of drug combination with metrinidazole was 599 times, 20.70% （124 case）of which was irrational. The most frequent combination was metrinidazole＋cefuroxime, while the most frequent irrational combination was metrinidazole＋cefperazone/sulbactam. CONCLUSIONS. Irrational drug combination of metronidazole has become a very common problem in clinic, especially in some special departments, which should be attached more importance by clinical medical staffs.
出处
《中国药房》
CAS
CSCD
2014年第8期744-746,共3页
China Pharmacy
关键词
甲硝唑
联合用药
合理用药
使用情况
Metronidazole
Drug combination
Rrational drug use
Application
