摘要
目的:分析湖北省荆门地区药品不良反应(ADR)发生的特点,为促进临床安全用药提供参考。方法:查阅荆门地区2012年上报国家药品不良反应监测中心的1 814份ADR报告,分别按报告单位、患者性别、药品种类、剂型、给药途径、ADR累及器官及系统等项目统计并分析。结果:1 814例报告中,来自医疗机构的报告占99.78%;ADR患者男女比例相当;引起ADR的药物以抗菌药多见,占59.59%,其中以β-内酰胺类构成比最高,占52.98%;引起ADR的给药途径以静滴多见,占78.78%;ADR累及以消化系统、皮肤及附件多见,分别占34.43%、32.12%。结论:各报告单位要重视ADR监测,不断提高ADR监测水平,降低ADR的发生风险。
Objective：To analyze the characteristics of adverse drug reaction （ADR） in Jingmen area of Hubei province and promote clinical rational drug use. Methods ：The report units, sex of the patients, types of ADR, drug varieties and result evaluation were analyzed from 1 814 ADR reports in Jingmen area. Results ：99.78% of the cases came from the medical institutions, the ratio of male to female was almost equal,ADRs were mainly caused by antibiotics（59.59% ）, and among the antibiotics the percent of 52.98 cases were caused by β-lactum. The main route of administration was caused by intravenous drip（78.78% ） , main clinical manifestations of ADRs were lesion of skin and its appendants, and digestive system accounting for 34.43% and 32.12% , respectively. Conclusion： Reporting institutions should pay attention to the monitoring of ADR, improve their monitoring level and reduce the risks of ADR occurrence.
出处
《药物流行病学杂志》
CAS
2014年第1期42-45,共4页
Chinese Journal of Pharmacoepidemiology
关键词
药品不良反应
报告
监测
合理用药
Adverse drug reaction
Reports
Monitoring
Rational drug use
