摘要
目的 研究舒血宁注射液对老年2型糖尿病合并颈动脉斑块患者血清同型半胱氨酸（Hcy）及高敏C反应蛋白（hs-CRP）的影响.方法 将42例老年糖尿病合并颈动脉斑块患者使用随机数字表法随机分为观察组和对照组,各21例.2组均给予常规治疗,观察组在此基础上加用舒血宁注射液治疗,20 ml/次,用0.9％氯化钠注射液或葡萄糖250 ml稀释后静脉滴注,1次/d,2周为1个疗程.2个疗程后观察治疗前后Hcy及hs-CRP指标的变化.结果 观察组患者治疗后血清Hcy及hs-CRP与治疗前及对照组治疗后比较均明显降低,差异均有统计学意义[（3.2±1.8） mg/L比（7.6±1.0）mg/L,（5.8±2.2） mg/L;（9.4±3.1） μmol/L比（17.1±2.6）μmol/L,（14.7±3.2）μmol/L]（均P＜0.05）.结论 舒血宁注射液可明显降低老年2型糖尿病合并颈动脉斑块患者血清hs-CRP及Hcy水平.
Objective To evaluate the effect of Shuxuening infection on the level of homocysteine （Hcy）and hypersensitive C-reactive protein （hs-CRP） in peripheral blood for the elderly patients with type 2 diabetes mellitus and carotid plaque.Methods Forty-two elderly patients were randomly divided into two groups.The observation group was given conventional therapy adding Shuxuening infection,while the control group was given conventional therapy only.After four weeks serum hs-CRP concentrations and homocysteine changes before and after the use of Shuxuening infection were compared.Results The levels of hs-CRP and Hcy in observation group after treatment were significantly lower than before the treatment and control group after treatment [（3.2 ± 1.8） mg/L vs （7.6± 1.0）mg/L,（5.8 ±2.2）mg/L;（9.4 ±3.1） μmol/L vs （17.1 ± 2.6） μmol/L,（14.7 ±3.2） μmol/L] （all P 〈 0.05）.Conclusion Shuxuening infection can decrease the serum concentration of Hcy and hs-CRP parameters in elderly patients with type 2 diabetes mellitus and carotid plaque.
出处
《中国医药》
2014年第2期196-198,共3页
China Medicine
