摘要
目的 分析声带后联合慢性炎性反应与阻塞型睡眠呼吸暂停低通气综合征（OSAHS）的相关性及对OSAHS的预测价值.方法 选择OSAHS患者156例,均行多导睡眠图（PSG）和纤维喉镜检查,根据声带后联合慢性炎性反应情况进行分度,分为轻度32例,中度70例,重度36例,极重度18例,比较不同程度患者呼吸暂停低通气指数（AHI）、最低血氧饱和度、平均血氧饱和度.对患者根据病因行对症治疗,于治疗后1,3个月判定疗效.结果 治疗前随着声带后联合慢性炎性反应程度的加重,AHI逐渐升高[轻度、中度、重度、极重度分别为（11.23±4.13）,（21.23±13.29）,（44.53±10.11）,（56.56±12.31）次/h],最低血氧饱和度和平均血氧饱和度逐渐下降（轻度、中度、重度、极重度分别为0.914 4±0.053 1和0.955 0±0.041 2,0.834 2±0.098 6和0.913 5±0.033 2,0.626 8±0.0904和0.863 1±0.053 2,0.601 1±0.101 1和0.752 1±0.040 1）,差异均有统计学意义（P＜0.05）.治疗后1个月总有效率为75.64％ （118/156）,治疗后3个月总有效率为88.46％（138/156）.结论 声带后联合慢性炎性反应程度与OSAHS程度呈正相关,OSAHS患者根据病因治疗有明显的效果.
Objective To analyze the correlation between chronic inflammation of vocal cords after the union and obstructive sleep apnea hypopnea syndrome （OSAHS）,the predictive value to OSAHS.Methods One hundred and fifty-six cases of OSAHS patients underwent polysomnography （PSG） and fiber laryngoscopy,indexing based on the chronic inflammatory of vocal cords after the union.Apnea-hypopnea index （AHI）,the lowest blood oxygen saturation and mean oxygen saturation were compared in different degrees patients.Mild,moderate,severe,very severe degree respectively had 32,70,36,18 cases.The patients were treated according to the cause and 1 and 3 months after treatment to determine efficacy.Results Following severity of chronic inflammation of vocal cords after the union,AHI gradually increased before treatment [mild,moderate,severe,very severe degree degree respectively （11.23 ±4.13）,（21.23 ± 13.29）,（44.53 ± 10.11）,（56.56 ± 12.31） times/h],the lowest oxygen saturation and mean oxygen saturation decreased （mild,moderate,severe,very severe degree respectively 0.914 4 ±0.053 1 and 0.955 0 ± 0.041 2,0.834 2 ± 0.098 6 and 0.913 5 ±0.033 2,0.626 8 ±0.090 4 and 0.863 1 ±0.053 2,0.601 1 ± 0.101 1 and 0.752 1 ± 0.040 1）,the differences were statistically significant （P 〈 0.05）.One month after treatment,the total effective rate was 75.64% （118/156）,3 months after treatment was 88.46% （138/156）.Conclusion Chronic inflammatory degree of vocal cords after the union is positively correlated with OSAHS,OSAHS patients according to etiological treatment have a significant effect.
出处
《中国医师进修杂志》
2014年第6期11-13,共3页
Chinese Journal of Postgraduates of Medicine
