摘要
目的观察布地奈德、万托林和异丙托溴铵气雾剂联合压缩雾化吸入治疗慢性阻塞性肺疾病(COPD)急性加重期的临床效果。方法选取2011年4月-2013年3月东莞市横沥医院呼吸科就诊的COPD急性加重期患者120例,COPD分级III^IV级,随机分为实验组和对照组,各60例。实验组给予布地奈德、万托林和异丙托溴铵气雾剂联合压缩雾化吸入治疗。对照组给予单纯布地奈德吸入治疗,比较两组治疗效果及不良反应情况。结果实验组有效率为98.33%,对照组有效率为75.00%,比较有统计学意义(P<0.05);实验组3例(5.0%)出现不良反应,对照组4例(6.7%)出现,比较无统计学意义。结论布地奈德、万托林和异丙托溴铵气雾剂联合压缩雾化吸入治疗COPD急性加重期较单纯布地奈德吸入疗效好,副作用较少。
Objective To observe the clinical effect of aerosol inhalation ofbudesonide combined ventolin and atrovent for treatment of chronic obstructive pulmonary disease（COPD） acute aggravating period. Methods 120 patients in COPD acute aggravating period with COPD ranking Ⅲ-Ⅳ coming to respiratory department of the hospital from April 2011 to March 2013 were selected and randomly divided into experiment group and＇control group both with 60 cases. Experiment group was given treatment of aerosol inhalation of budesonide combined ventolin and atrovent and control group was given pure aerosol inhalation of budesonide. Curative effects and adverse reactions of both groups were compared. Results Effective rate of experiment group was 98.33% and control group was 75.00% （P〈0.05）. Adverse reaction occurred in 3 cases in experiment group and 4 cases in control group. Conclusion Aerosol inhalation ofbudesonide combined ventolin and atrovent for treatment of COPD acute aggravating period has a better curative effect than pure aerosol inhalation of budesonide with fewer adverse reactions.
出处
《当代医学》
2014年第8期5-6,共2页
Contemporary Medicine
关键词
慢性阻塞性肺疾病
布地奈德
联合压缩
Chronic obstructive pulmonary disease
Budesonide
Joint compression
