摘要
目的探讨CysC(胱抑素C)、β2微球蛋白(β2-MG)、Cr(肌酐)、Urea(尿素)等检测肾功能损害指标的敏感度及胃癌患者化疗后肾脏早期损害应用价值。方法分析比较用贝克曼AU5811全自动生化分析仪对112例胃癌患者化疗前后血清CysC、β2-MG、Cr、Urea结果。结果胃癌患者化疗后血清CysC、β2-MG、Cr、Urea分别为3.42±0.43、2.96±0.55、100.7±12.1、6.12±0.90,其敏感性依次为CysC、β2-MG、Cr、Urea。结论胃癌患者化疗后,CysC、β2-MG对肾脏早期损害有着较好的诊断作用,是肾脏早期损害的最佳指标,优于传统肾功检测项目Urea、Cr。
Objective To explore the diagnostic effect of combined detection of CysC, β2-MG, Cr and Urea on early renal damage in gastric cancer patients after chemotherapy. Methods The contents of Serum CysC, β2-MG, Cr and Urea of 112 gastric cancer patients before and after chemotherapy were detected by Beckmann full automatic biochemical analyzer AU5811. Results The contents of CysC, β2-MG, Cr and Urea were 3.42±0.43, 2.96±0.55, 100.7±12.1 and 6.12±0.90 respectively, and the sensibility of them were CysC, β2-MG, Cr and Urea in order. Conclusion After chemotherapy for gastric cancer patients, Cy- sC and β2-MG can act as good diagnostic indexes for early renal damage and were superior to Urea and Cr.
出处
《山东医学高等专科学校学报》
2014年第1期49-51,共3页
Journal of Shandong Medical College
