摘要
目的 评价实时超声弹性成像定量参数评价颈动脉粥样斑块的价值.方法 选择2011年5月～2013年6月在浙江省嘉兴市中医医院就诊的颈动脉粥样斑块患者92例患者,共检出129个颈动脉硬化斑块,按照斑块性质分为3组：软斑块组（39个斑块）、混合性斑块组（54个斑块）、硬斑块组（36个斑块）,分别对各个斑块行超声弹性成像技术检查,记录并比较各个斑块感兴趣区弹性应变值（ROI A值）及应变率（SR）.采用超声弹性成像评分评价各组斑块,并分析与ROI A值及SR值的相关性.结果 ①三组斑块的ROI A值及SR值比较差异均有高度统计学意义（F=167.034、886.361,P＜0.01）.其中软斑块组ROI A值（0.0029±0.0008）高于混合性斑块组（0.0016±0.0007）及硬斑块组（0.0002±0.0001）,差异均有高度统计学意义（t=0.0013、0.0027,P＜0.01）;混合性斑块组ROIA值高于硬斑块组,差异有高度统计学意义（t=0.0014,P＜0.01）.软斑块组SR值（2.18±0.40）低于混合性斑块组（5.61±2.29）及硬斑块组（44.69±8.88）,差异有高度统计学意义（t=3.43、42.51,P＜0.01）;混合性斑块组SR值低于硬斑块组,差异有高度统计学意义（t=39.08,P＜0.01）.②三组弹性评分各分值所占比例差异有统计学意义（x2=5.62,P＜ 0.05）;其中软斑块组与混合性斑块组、硬斑块组弹性评分各分值所占比例比较,差异均有统计学意义（x2=4.76、6.91,P＜0.05）;混合性斑块组与硬斑块组弹性评分各分值所占比例比较,差异均有统计学意义（x2=8.51,P＜ 0.05）.③斑块弹性评分与斑块ROI A值及SR值均成正相关性（r=0.758、0.835,P＜0.05）.结论 超声弹性成像斑块弹性ROI A值及SR可以定量反映不同类型颈动脉斑块质地,可以作为常规超声评估斑块稳定的组织学参考.
Objective To evaluate the value of real-time ultrasound elastography quantitative parameters in estimating the carotid artery plaque.Methods 92 cases of carotid artery plaque in Traditional Chinese Medicine Hospital of Jiaxing City from May 2011 to June 2013 were selected,129 carotid artery plaque were checked out and divided into 3 groups according to the nature of plaque with 39 cases in soft plaque group,54 cases in mixed plaque group,36 cases in hard plaque group; each plaque was checked by ultrasonic elastography,ROI A and SR value of region of interest were recorded and compared.Elasticity imaging score was used to evaluate the plaque in each group,the correlation among the elasticity imaging score and ROI A,SR value was analyzed.Results ①The differences of ROI A,SR value in the three groups were statistically significant （F =167.034,886.361,P 〈 0.01）.ROI A value in soft plaque group （0.0029±0.0008） was higher than that in mixed plaque group （0.0016±0.0007） and hard plaque group （0.0002±0.0001）,the differences were statistically significant （t =0.0013,0.0027,P 〈 0.01）; ROI A value in mixed plaque group was higher than that in hard plaque group,the differences were statistically significant （t =0.0014,P 〈 0.01）.SR value in soft plaque group （2.18±0.40） was lower than that in mixed plaque group （5.61±2.29） and hard plaque group （44.69±8.88）,the differences were statistically significant （t =3.43,42.51,P 〈 0.01）; SR value in mixed plaque group was lower than that in hard plaque group,the differences were statistically significant （t =39.08,P 〈 0.01）.②The differences of elasticity score proportion in three groups were statistically significant （x 2 =5.62,P 〈 0.05）; the differences of elasticity score proportion in soft plaque group compared with mixed plaque group and hard plaque group was statistically significant （x2 =4.76、6.91,P 〈 0.05）; the differences of elasticity score proportion in mixed plaque group and hard plaque group was statistically significant （x2 =8.51,P 〈0.05）.③The positive correlation was found among elasticity score and ROI A value,SR value （r =0.758,0.835,P 〈0.05）.Conclusion Ultrasonic elasticity imaging plaques ROI A value and SR value can quantitatively reflect the different types of carotid plaques texture,it is right to make the ultrasound assessment of plaque stability as a histologic reference.
出处
《中国医药导报》
CAS
2014年第8期98-100,104,共4页
China Medical Herald
基金
浙江省嘉兴市科技计划项目(编号2012AY1072-1)
关键词
实时超声
弹性成像
应变率
Real-time ultrasound
Elasticity imaging
Strain rate
