摘要
目的超声速度向量成像(velocity vector imaging,VVI)技术是近年来超声检查的一项新技术,多用于评价心肌及血管内膜功能,应用于短暂性脑缺血发作(transient ischemic attack,TIA)方面研究较少。观察TIA患者颈动脉管壁运动及斑块稳定性,为临床防治TIA提供依据。方法收集30例TIA患者,分为TIA-1组(未检出斑块)及TIA-2组(检出斑块),以30例体检者为对照,分为对照Ⅰ组(未检出斑块)及对照Ⅱ组(检出斑块)。应用VVI技术检测连续3个心动周期颈动脉短轴切面及长轴切面血管内膜二维动态运动速度向量图;获取短轴切面相应位点内膜收缩期最大运动速度(maximum velocity,Vmax)、最大切向应变(maximum tangential strain,Smax)及最大切向应变率(maximum tangential strain rate,SR-max);同时获取长轴切面各位点纵向最大运动速度、纵向应变及纵向应变率。结果与对照各组比较,TIA各组患者二维速度向量图显示斑块内膜运动速度向量大小、方向及时相较对照各组明显紊乱;TIA-1组、TIA-2组1、2、3点颈动脉短轴及长轴切面运动速度[(6.98±1.37)×10-2cm/s、(6.70±0.83)×10-2cm/s、(5.93±1.65)×10-2cm/s;(4.87±0.97)×10-2cm/s、(5.78±0.72)×10-2cm/s、(3.98±0.83)×10-2cm/s]、应变[(4.61±0.92)%、(4.44±1.08)%、(3.65±0.99)%;(3.42±1.01)%、(3.59±1.23)%、(2.98±0.69)%]及应变率[(0.30±0.05)/S、(0.32±0.07)/S、(0.29±0.08)/S;(0.21±0.08)/S、(0.25±0.07)/S、(0.21±0.08)/S]均低于对照各组,差异有统计学意义(P<0.05),尤以TIA-2组降低更显著(P<0.01);TIA-1组、TIA-2组长轴切面1点运动速度、应变及应变率均低于2、3点,差异有统计学意义(P<0.05)。结论 VVI技术可通过综合分析评价TIA患者颈动脉管壁运动及斑块稳定性,为临床防治TIA提供理论依据。
Objective Velocity vector imaging （VVI） is a new technology for assessing myocardial and vascular functions, but less applied to the study of transient ischemic attack （TIA）. The authors observed the carotid wall motion and plaque stability in TIA patients to provide some evidence for the clinical prevention and treatment of TIA.MethodsThirty TIA patients were divided into TIA group-1 （with no detectable plaque） and TIA group 2 （with detectable plaque）, and another 30 healthy volunteers assigned to control group 1 （with no detectable plaque） and control group 2 （with detectable plaque）. Two-dimensional dynamic images of 3 short axis views and longitudinal axis views of the vascular intima systolic maximum velocity （Vmax）, maximum tangential strain （Smax） and maximum tangential strain rate （SR-max） were obtained by VVI.ResultsCompared with the healthy controls, the TIA patients showed evident disorder and asynchrony of the intima velocity vectors, with significantly lower Vmax, Smax and SRmax of the carotid short axis views and longitudinal axis views at the 1st, 2nd and 3rd point （P〈0.05）, even more significantly in TIA group 2 （[3.42±1.01]%, [0.30±0.05]/S, [4.87±0.97]×10-2cm/s）（P〈0.01）. The Vmax, Smax and SRmax of the longitudinal axis views were remarkably lower at the 1st than at the 2nd （P〈0.05） and 3rd point （P〈0.01） in the TIA patients.ConclusionVVI allows a comprehensive analysis and evaluation of the carotid wall motion and plaque stability in TIA pati
出处
《医学研究生学报》
CAS
北大核心
2014年第2期166-170,共5页
Journal of Medical Postgraduates
基金
贵州省科技厅科学技术基金(黔科合J字LKZ[2010]21号)
