摘要
目的探讨三餐前门冬胰岛素联合中效胰岛素对妊娠糖尿病患者的疗效。方法选择需要胰岛素治疗的妊娠糖尿病40例,通过Excel生成随机数表分为两组,A组采用三餐前门冬胰岛素联合睡前中效胰岛素治疗;B组采用三餐前0.5 h常规人胰岛素联合睡前(22:00)中效胰岛素治疗;比较治疗后两组空腹血糖、餐后2 h血糖、胰岛素用量、低血糖发生率。结果 A组治疗后餐后血糖控制更理想,低血糖发生率低,优于B组(P<0.05)。结论妊娠期糖尿病患者采用门冬胰岛素联合中效胰岛素治疗,低血糖发生率低,降糖效果显著,安全性高。
Objective To investigate the effect of insulin aspart before meals combined with intermediate-acting insulin on the pa- tients suffering from gestational diabetes. Methods A total of 40 patients suffering from gestational diabetes and needed insulin therapy were divided into two groups at random via excel table. Group A was treated with insulin aspart before meals and intermedi- ate-acting insulin at bedtime （ 10 p. m. ） , and Group B with regular insulin half an hour before meals and intel^nediate-acting insu- lin at bedtime （10 p. m. ）. Such indexes, as fasting plasma glucose, 2-hour postprandial glucose, insulin dosage and the incidence of hypoglycemia, were observed. Results After therapy, the control of postprandial glucose of Group A is better and the incidence of hypoglycemia is lower （P 〈 0.05）. Conclusion On the treatment of gestational diabetes, insulin aspart before meals combined with intermediate-acting insulin has the superiority of lower incidence of hypoglycemia, significant effect on blood sugar control and high safety.
出处
《临床军医杂志》
CAS
2014年第3期238-239,共2页
Clinical Journal of Medical Officers
关键词
妊娠糖尿病
门冬胰岛素
疗效
gestational diabetes mellitus
insulin aspart
threapeutic effect
