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甲状腺球蛋白水平与分化型甲状腺癌转移灶的关系 被引量:12

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摘要 目的了解甲状腺球蛋白(TG)与分化型甲状腺癌转移灶的关系,评价TG的诊断价值。方法回顾性分析分化型甲状腺癌患者的TG水平,选取199例患者,均为术后、131I清甲治疗后并排除TgA阳性及失分化的患者,把患者分为无转移、淋巴结转移、颈部软组织侵犯、肺部转移、骨及其他脏器转移5组,比较之间的差异性。结果 (1)无转移组TG值与其他各组进行统计学分析,除颈部软组织侵犯组(2=-14.14,P=0.131),其余各组均差异有统计学意义(2=-44.01、-83.85、-104.38,P=0.000、0.00、0.00)。(2)TG水平在颈部软组织侵犯组、颈部淋巴结转移、肺转移、骨及其他脏器转移逐渐增高(秩次值依次66.45、96.33、136.17、156.69),TG值与部位正相关(P=0.000)。(3)各组的TG值与转移灶大小进行相关性分析,在各组中两者都正相关(依次P=0.009、0.000、0.002、0.001)。(4)各组TG值与转移灶数目进行相关性分析,除软组织的病灶数目均为1个,其余各组中两者都正相关(依次P=0.042、0.000、0.001)。结论颈部软组织侵犯及较小的淋巴结转移时,TG值的诊断价值不高;TG值对肺部转移组、骨及其他脏器转移的患者的诊断价值较高。病灶越大,数量越多,TG值越高;病灶越小,数量越少,TG值越低。
出处 《广东医学》 CAS CSCD 北大核心 2014年第6期878-881,共4页 Guangdong Medical Journal
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共引文献108

同被引文献130

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