摘要
目的:探讨老年胃癌患者手术后三维适形放射治疗(放疗)同步XELOX化学治疗(化疗)的临床价值。方法:选取我院2年内的胃癌根治术老年患者104例,分别在术后行单纯XELOX化疗与同时三维适形放疗。结果:研究组患者1年内转移率与对照组无明显差异(P>0.05),复发率明显低于对照组(P<0.05),3年内生存率均显著高于对照组(P<0.05),治疗中毒副反应略高于对照组,但无明显差异(P>0.05)。结论:胃癌术后行三维适形放疗同步XELOX化疗能够显著降低术后复发率,提高患者术后生存率,同时无明显毒副反应增加,保持较低的转移率,具有较高的临床价值。
Objective：To investigate the clinical value of post-operative three dimensional conformal radiotherapy synchronization XELOX chemotherapy on elderly patients with gastric cancer.Methods：104 elderly gastric cancer patients accepted gastrectomy in our hospital in recent two years were assigned to receive simple XELOX chemotherapy or XELOX synchronized three dimensional conformal radiotherapy after surgery. Results：There was no significant difference （P〉0.05） in the one year metastasis rate of patients between the two groups. The recurrence rate in the study group was significantly lower （P〈0.05） and 3 year survival rate was significantly higher （P〈0.05） than the control group. The toxicity effects were slightly higher in the study group but no significant difference was found （P〉0.05）. Conclusion：Postoperative three dimensional conformal radiotherapy synchronized XELOX chemotherapy can significantly reduce the recurrence rate and improve the survival rate of elderly patients with gastric cancer, while no obvious increase of toxicity effects was observed and the metastasis rate kept low. This treatment had a high clinical value.
出处
《中国医药导刊》
2013年第12期2006-2007,共2页
Chinese Journal of Medicinal Guide
关键词
老年胃癌患者
术后三维适形放疗
同步化疗
XELOX方案
Elderly patient
Gastric cancer
Post-operative three dimensional conformal radiotherapy
Synchronized chemotherapy
Xelox regime
