摘要
目的探讨复方卡力孜然酊应用于白癜风治疗的安全性及临床疗效。方法将86例白癜风患者纳入研究，按数字表法随机分为两组，对照组43例采用窄谱中波紫外线（NB—UVB）照射治疗，观察组43例采用复方卡力孜然酊辅助NB．UVB照射治疗，观察两组的皮损疗效和皮肤病生活质量（DLQI）评分。结果观察组第1、第2、第3疗程总有效率分别为32．56％、58．14％、81．40％，均高于对照组的25．58％、41．86％、60．47％，组间第3疗程的总有效率差异有统计学意义（X^2=4．568，P〈0．05）；观察组治疗第1、第2、第3疗程后的DLQI评分均明显低于对照组（X^2=1．916、t2=4．298、t3=4．661，均P〈0．05）；观察组、对照组的不良反应发生率分别为16．28％、11．63％，组间差异无统计学意义（x。=0．387，P〉0．05）。结论复方卡力孜然酊辅助治疗白癜风有较好的临床疗效，能提高患者生活质量，不良反应轻微。
Objective To investigate the safety and effectiveness of compound card force cumin tincture in the treatment of vitiligo. Methods The 86 cases of vitiligo patients included in the study were randomly divided into two groups, observation group （n = 43 ） and control group （n = 43 ）. The observation group was given narrow-band ul- traviolet B irradiation and compound card force cumin tincture, and the control group was only given narrow-band ul- traviolet B irradiation. The clinical efficacy and the dermatology life quality index（DLQI） in two groups were observed and compared. Results The total efficiency rate after lst,2nd,3rd course of treatment in the observation group were higher than those of the control group, and the total efficiency rate after 3rd course of treatment in the observation group was significantly higher than that of the control group（ X^2 = 4. 568 ,P 〈 0.05 ） ;the DLQI scores after l st,2nd, 3rd course of treatment in the observation group were significantly lower than those of the control group（t1 = 1. 916, t2 =4. 298 ,t3 =4.661 ,P 〈 0.05 ）;the incidence of adverse reactions 16.28% in the observation group between the control group 11.63 % showed no significant difference （ X2 = 0. 387, P 〉 0.05 ）. Conclusion Compound card force cumin tincture in the treatment of vitilizo has more clinical superiority.
出处
《中国基层医药》
CAS
2014年第7期997-999,共3页
Chinese Journal of Primary Medicine and Pharmacy
关键词
白癜风
复方卡力孜然酊
皮肤病生活质量指数
Vitiligo
Compound card force cumin tincture
Lesions efficacy
DLQI scores
