摘要
耳鸣是临床耳鼻喉科一大顽疾,有关耳鸣形成的假说很多,但均不能解释所有的耳鸣现象。目前认为耳鸣是一种以中枢和外周神经病变为主的多因素作用的结果,近年来国内外研究表明耳鸣的发生与听觉中枢可塑性不良改变密切相关。本文对近年来有关耳鸣与中枢神经可塑性的相关研究进行综述,以期为临床耳鸣的治疗提供新的作用靶点和可能干预策略。
Tinnitus is one of stubborn diseases in otolaryngology,and there exist lots of hypotheses about it,but no one can explain the occurrence of all tinnitus.Now tinnitus is generally considered as a result caused by central and peripheral lesions,and other factors.Recently,domestic and international studies have shown that the occurrence of tinnitus is closely related to abnormal plasticity changes in auditory center.This paper reviews recent researches about neuroplasticity changes during tinnitus to provide therapeutic targets and possible intervention strategies for clinical treatment of tinnitus.
出处
《中国全科医学》
CAS
CSCD
北大核心
2014年第8期955-959,共5页
Chinese General Practice
基金
三峡大学医学院大学生科技创新项目(2013YCX012)
关键词
耳鸣
中枢神经系统
受体
神经递质
综述
Tinnitus
Central nervous system
Receptors,neurotransmitter
Review
